TY - JOUR AU - Siegel, R. L. AU - Miller, K. D. AU - Jemal, A. PY - 2016 DA - 2016// TI - Cancer statistics JO - Ca Cancer J Clin. VL - 66 UR - https://doi.org/10.3322/caac.21332 DO - 10.3322/caac.21332 ID - Siegel2016 ER - TY - JOUR AU - Kilfoy, B. A. AU - Devesa, S. S. AU - Ward, M. H. AU - Zhang, Y. AU - Rosenberg, P. S. AU - Holford, T. R. PY - 2009 DA - 2009// TI - Gender is an age-specific effect modifier for papillary cancers of the thyroid gland JO - Cancer Epidemiol Biomarkers Prev. VL - 18 UR - https://doi.org/10.1158/1055-9965.EPI-08-0976 DO - 10.1158/1055-9965.EPI-08-0976 ID - Kilfoy2009 ER - TY - JOUR AU - Xing, M. AU - Haugen, B. R. AU - Schlumberger, M. PY - 2013 DA - 2013// TI - Progress in molecular-based management of differentiated thyroid cancer JO - Lancet. VL - 381 UR - https://doi.org/10.1016/S0140-6736(13)60109-9 DO - 10.1016/S0140-6736(13)60109-9 ID - Xing2013 ER - TY - JOUR AU - Caronia, L. M. AU - Phay, J. E. AU - Shah, M. H. PY - 2011 DA - 2011// TI - Role of BRAF in thyroid oncogenesis JO - Clin Cancer Res. VL - 17 UR - https://doi.org/10.1158/1078-0432.CCR-11-1155 DO - 10.1158/1078-0432.CCR-11-1155 ID - Caronia2011 ER - TY - JOUR AU - Xing, M. PY - 2005 DA - 2005// TI - BRAF mutation in thyroid cancer JO - Endocr Relat Cancer. VL - 12 UR - https://doi.org/10.1677/erc.1.0978 DO - 10.1677/erc.1.0978 ID - Xing2005 ER - TY - JOUR AU - Gómez-Sáez, J. M. PY - 2011 DA - 2011// TI - Diagnostic and prognostic markers in differentiated thyroid cancer JO - Curr Genomics. VL - 12 UR - https://doi.org/10.2174/138920211798120826 DO - 10.2174/138920211798120826 ID - Gómez-Sáez2011 ER - TY - JOUR AU - Fagin, J. A. AU - Wells, S. A. PY - 2016 DA - 2016// TI - Biologic and clinical perspectives on thyroid cancer JO - N Engl J Med VL - 375 UR - https://doi.org/10.1056/NEJMra1501993 DO - 10.1056/NEJMra1501993 ID - Fagin2016 ER - TY - JOUR AU - Kim, T. H. AU - Park, Y. J. AU - Lim, J. A. AU - Ahn, H. Y. AU - Lee, E. K. AU - Lee, Y. J. PY - 2012 DA - 2012// TI - The association of the BRAF (V600E) mutation with prognostic factors and poor clinical outcome in papillary thyroid cancer: a meta-analysis JO - Cancer. VL - 118 UR - https://doi.org/10.1002/cncr.26500 DO - 10.1002/cncr.26500 ID - Kim2012 ER - TY - JOUR AU - Liu, X. AU - Qu, S. AU - Liu, R. AU - Sheng, C. AU - Shi, X. AU - Zhu, G. PY - 2014 DA - 2014// TI - TERT promoter mutations and their association with BRAF V600E mutation and aggressive clinicopathological characteristics of thyroid cancer JO - J Clin Endocrinol Metab. VL - 99 UR - https://doi.org/10.1210/jc.2013-4048 DO - 10.1210/jc.2013-4048 ID - Liu2014 ER - TY - JOUR AU - Sancisi, V. AU - Nicoli, D. AU - Ragazzi, M. AU - Piana, S. AU - Ciarrocchi, A. PY - 2012 DA - 2012// TI - BRAFV600E mutation does not mean distant metastasis in thyroid papillary carcinomas JO - J Clin Endocrinol Metab. VL - 97 UR - https://doi.org/10.1210/jc.2012-1526 DO - 10.1210/jc.2012-1526 ID - Sancisi2012 ER - TY - JOUR AU - Nam, J. K. AU - Jung, C. K. AU - Song, B. J. AU - Lim, D. J. AU - Chae, B. J. AU - Lee, N. S. PY - 2012 DA - 2012// TI - Is the BRAF(V600E) mutation useful as a predictor of preoperative risk in papillary thyroid cancer? JO - Am J Surg. VL - 203 UR - https://doi.org/10.1016/j.amjsurg.2011.02.013 DO - 10.1016/j.amjsurg.2011.02.013 ID - Nam2012 ER - TY - JOUR AU - Czarniecka, A. AU - Kowal, M. AU - Rusinek, D. AU - Krajewska, J. AU - Jarzab, M. AU - Stobiecka, E. PY - 2015 DA - 2015// TI - The risk of relapse in papillary thyroid cancer (PTC) in the context of BRAFV600E mutation status and other prognostic factors JO - PLoS One. VL - 10 UR - https://doi.org/10.1371/journal.pone.0132821 DO - 10.1371/journal.pone.0132821 ID - Czarniecka2015 ER - TY - JOUR AU - Xing, M. AU - Usadel, H. AU - Cohen, Y. AU - Tokumaru, Y. AU - Guo, Z. AU - Westra, W. B. PY - 2003 DA - 2003// TI - Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing JO - Cancer Res. VL - 63 ID - Xing2003 ER - TY - JOUR AU - Xing, M. AU - Tokumaru, Y. AU - Wu, G. AU - Westra, W. B. AU - Ladenson, P. W. AU - Sidransky, D. PY - 2003 DA - 2003// TI - Hypermethylation of the Pendred syndrome gene SLC26A4 is an early event in thyroid tumorigenesis JO - Cancer Res. VL - 63 ID - Xing2003 ER - TY - JOUR AU - Schagdarsurengin, U. AU - Gimm, O. AU - Hoang-Vu, C. AU - Dralle, H. AU - Pfeifer, G. P. AU - Dammann, R. PY - 2002 DA - 2002// TI - Frequent epigenetic silencing of the CpG island promoter of RASSF1A in thyroid carcinoma JO - Cancer Res. VL - 62 ID - Schagdarsurengin2002 ER - TY - JOUR AU - Brait, M. AU - Loyo, M. AU - Rosenbaum, E. AU - Ostrow, K. L. AU - Markova, A. AU - Papagerakis, S. PY - 2012 DA - 2012// TI - Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer JO - Epigenetics. VL - 7 UR - https://doi.org/10.4161/epi.20524 DO - 10.4161/epi.20524 ID - Brait2012 ER - TY - JOUR AU - Hou, P. AU - Liu, D. AU - Xing, M. PY - 2011 DA - 2011// TI - Genome-wide alterations in gene methylation by the BRAF V600E mutation in papillary thyroid cancer cells JO - Endocr Relat Cancer. VL - 18 UR - https://doi.org/10.1530/ERC-11-0212 DO - 10.1530/ERC-11-0212 ID - Hou2011 ER - TY - JOUR AU - Kikuchi, Y. AU - Tsuji, E. AU - Yagi, K. AU - Matsusaka, K. AU - Tsuji, S. AU - Kurebayashi, J. PY - 2013 DA - 2013// TI - Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation JO - Front Genet. VL - 4 UR - https://doi.org/10.3389/fgene.2013.00271 DO - 10.3389/fgene.2013.00271 ID - Kikuchi2013 ER - TY - JOUR AU - Mancikova, V. AU - Buj, R. AU - Castelblanco, E. AU - Inglada-Pérez, L. AU - Diez, A. AU - Cubas, A. A. PY - 2014 DA - 2014// TI - DNA methylation profiling of welldifferentiated thyroid cancer uncovers markers of recurrence free survival JO - Int J Cancer. VL - 135 UR - https://doi.org/10.1002/ijc.28703 DO - 10.1002/ijc.28703 ID - Mancikova2014 ER - TY - JOUR AU - Ellis, R. J. AU - Wang, Y. AU - Stevenson, H. S. AU - Boufraqech, M. AU - Patel, D. AU - Nilubol, N. PY - 2014 DA - 2014// TI - Genome-wide methylation patterns in papillary thyroid cancer are distinct based on histological subtype and tumor genotype JO - J Clin Endocrinol Metab. VL - 9 UR - https://doi.org/10.1210/jc.2013-2749 DO - 10.1210/jc.2013-2749 ID - Ellis2014 ER - TY - JOUR PY - 2014 DA - 2014// TI - Integrated genomic characterization of papillary thyroid carcinoma JO - Cell VL - 159 UR - https://doi.org/10.1016/j.cell.2014.09.050 DO - 10.1016/j.cell.2014.09.050 ID - ref21 ER - TY - JOUR AU - Rodríguez-Rodero, S. AU - Fernández, A. F. AU - Fernández-Morera, J. L. AU - Castro-Santos, P. AU - Bayon, G. F. AU - Ferrero, C. PY - 2013 DA - 2013// TI - DNA methylation signatures identify biologically distinct thyroid cancer subtypes JO - J Clin Endocrinol Metab. VL - 98 UR - https://doi.org/10.1210/jc.2012-3566 DO - 10.1210/jc.2012-3566 ID - Rodríguez-Rodero2013 ER - TY - JOUR AU - White, M. G. AU - Nagar, S. AU - Aschebrook-Kilfoy, B. AU - Jasmine, F. AU - Kibriya, M. G. AU - Ahsan, H. PY - 2016 DA - 2016// TI - Epigenetic alterations and canonical pathway disruption in papillary thyroid cancer: a genome-wide methylation analysis JO - Ann Surg Oncol. VL - 23 UR - https://doi.org/10.1245/s10434-016-5185-4 DO - 10.1245/s10434-016-5185-4 ID - White2016 ER - TY - JOUR AU - Sandoval, J. AU - Heyn, H. AU - Moran, S. AU - Serra-Musach, J. AU - Pujana, M. A. AU - Bibikova, M. PY - 2011 DA - 2011// TI - Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome JO - Epigenetics. VL - 6 UR - https://doi.org/10.4161/epi.6.6.16196 DO - 10.4161/epi.6.6.16196 ID - Sandoval2011 ER - TY - JOUR AU - Jones, P. A. PY - 2012 DA - 2012// TI - Functions of DNA methylation: islands, start sites, gene bodies and beyond JO - Nat Rev Genet. VL - 13 UR - https://doi.org/10.1038/nrg3230 DO - 10.1038/nrg3230 ID - Jones2012 ER - TY - JOUR AU - Barros-Filho, M. C. AU - Marchi, F. A. AU - Pinto, C. A. AU - Rogatto, S. R. AU - Kowalski, L. P. PY - 2015 DA - 2015// TI - High diagnostic accuracy based on CLDN10, HMGA2, and LAMB3 transcripts in papillary thyroid carcinoma JO - J Clin Endocrinol Metab. VL - 100 UR - https://doi.org/10.1210/jc.2014-4053 DO - 10.1210/jc.2014-4053 ID - Barros-Filho2015 ER - TY - JOUR AU - Ambatipudi, S. AU - Cuenin, C. AU - Hernandez-Vargas, H. AU - Ghantous, A. AU - Calvez-Kelm, F. L. AU - Kaaks, R. PY - 2016 DA - 2016// TI - Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study JO - Epigenomics. VL - 8 UR - https://doi.org/10.2217/epi-2016-0001 DO - 10.2217/epi-2016-0001 ID - Ambatipudi2016 ER - TY - JOUR AU - Ritchie, M. E. AU - Phipson, B. AU - Wu, D. AU - Hu, Y. AU - Law, C. W. AU - Shi, W. PY - 2015 DA - 2015// TI - limma powers differential expression analyses for RNA-sequencing and microarray studies JO - Nucleic Acids Res VL - 43 UR - https://doi.org/10.1093/nar/gkv007 DO - 10.1093/nar/gkv007 ID - Ritchie2015 ER - TY - JOUR AU - Maunakea, A. K. AU - Chepelev, I. AU - Zhao, K. PY - 2010 DA - 2010// TI - Epigenome mapping in normal and disease States JO - Circ Res. VL - 107 UR - https://doi.org/10.1161/CIRCRESAHA.110.222463 DO - 10.1161/CIRCRESAHA.110.222463 ID - Maunakea2010 ER - TY - JOUR AU - Sur, I. AU - Taipale, J. PY - 2016 DA - 2016// TI - The role of enhancers in cancer JO - Nat Rev Cancer. VL - 16 UR - https://doi.org/10.1038/nrc.2016.62 DO - 10.1038/nrc.2016.62 ID - Sur2016 ER - TY - JOUR AU - Schmidl, C. AU - Klug, M. AU - Boeld, T. J. AU - Andreesen, R. AU - Hoffmann, P. AU - Edinger, M. PY - 2009 DA - 2009// TI - Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity JO - Genome Res. VL - 19 UR - https://doi.org/10.1101/gr.091470.109 DO - 10.1101/gr.091470.109 ID - Schmidl2009 ER - TY - JOUR AU - Aran, D. AU - Hellman, A. PY - 2013 DA - 2013// TI - DNA methylation of transcriptional enhancers and cancer predisposition JO - Cell. VL - 154 UR - https://doi.org/10.1016/j.cell.2013.06.018 DO - 10.1016/j.cell.2013.06.018 ID - Aran2013 ER - TY - JOUR AU - Kondo, T. AU - Ezzat, S. AU - Asa, S. L. PY - 2006 DA - 2006// TI - Pathogenetic mechanisms in thyroid follicular-cell neoplasia JO - Nat Rev Cancer. VL - 6 UR - https://doi.org/10.1038/nrc1836 DO - 10.1038/nrc1836 ID - Kondo2006 ER - TY - JOUR AU - Niederreither, K. AU - Dollé, P. PY - 2008 DA - 2008// TI - Retinoic acid in development: towards an integrated view JO - Nat Rev Genet. VL - 9 UR - https://doi.org/10.1038/nrg2340 DO - 10.1038/nrg2340 ID - Niederreither2008 ER - TY - JOUR AU - Kropotova, E. S. AU - Zinovieva, O. L. AU - Zyryanova, A. F. AU - Dybovaya, V. I. AU - Prasolov, V. S. AU - Beresten, S. F. PY - 2014 DA - 2014// TI - Altered expression of multiple genes involved in retinoic acid biosynthesis in human colorectal cancer JO - Pathol Oncol Res. VL - 20 UR - https://doi.org/10.1007/s12253-014-9751-4 DO - 10.1007/s12253-014-9751-4 ID - Kropotova2014 ER - TY - JOUR AU - Kumar, S. AU - Sandell, L. L. AU - Trainor, P. A. AU - Koentgen, F. AU - Duester, G. PY - 2012 DA - 2012// TI - Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout models JO - Biochim Biophys Acta. VL - 182 UR - https://doi.org/10.1016/j.bbalip.2011.04.004 DO - 10.1016/j.bbalip.2011.04.004 ID - Kumar2012 ER - TY - JOUR AU - Schmutzler, C. AU - Winzer, R. AU - Meissner-Weigl, J. AU - Köhrle, J. PY - 1997 DA - 1997// TI - Retinoic acid increases sodium/iodide symporter mRNA levels in human thyroid cancer cell lines and suppresses expression of functional symporter in nontransformed FRTL-5 rat thyroid cells JO - Biochem Biophys Res Commun. VL - 240 UR - https://doi.org/10.1006/bbrc.1997.7715 DO - 10.1006/bbrc.1997.7715 ID - Schmutzler1997 ER - TY - JOUR AU - Kim, W. G. AU - Kim, E. Y. AU - Kim, T. Y. AU - Ryu, J. S. AU - Hong, S. J. AU - Kim, W. B. PY - 2009 DA - 2009// TI - Redifferentiation therapy with 13-cis retinoic acids in radioiodine-resistant thyroid cancer JO - Endocr J. VL - 56 UR - https://doi.org/10.1507/endocrj.K08E-254 DO - 10.1507/endocrj.K08E-254 ID - Kim2009 ER - TY - JOUR AU - Filetti, S. AU - Bidart, J. M. AU - Arturi, F. AU - Caillou, B. AU - Russo, D. AU - Schlumberger, M. PY - 1999 DA - 1999// TI - Sodium/iodide symporter: a key transport system in thyroid cancer cell metabolism JO - Eur J Endocrinol. VL - 141 UR - https://doi.org/10.1530/eje.0.1410443 DO - 10.1530/eje.0.1410443 ID - Filetti1999 ER - TY - JOUR AU - Grose, R. AU - Dickson, C. PY - 2005 DA - 2005// TI - Fibroblast growth factor signaling in tumorigenesis JO - Cytokine Growth Factor Rev. VL - 16 UR - https://doi.org/10.1016/j.cytogfr.2005.01.003 DO - 10.1016/j.cytogfr.2005.01.003 ID - Grose2005 ER - TY - JOUR AU - Eggo, M. C. AU - Hopkins, J. M. AU - Franklyn, J. A. AU - Johnson, G. D. AU - Sanders, D. S. AU - Sheppard, M. C. PY - 1995 DA - 1995// TI - Expression of fibroblast growth factors in thyroid cancer JO - J Clin Endocrinol Metab. VL - 80 ID - Eggo1995 ER - TY - JOUR AU - Boelaert, K. AU - McCabe, C. J. AU - Tannahill, L. A. AU - Gittoes, N. J. AU - Holder, R. L. AU - Watkinson, J. C. PY - 2003 DA - 2003// TI - Pituitary tumor transforming gene and fibroblast growth factor-2 expression: potential prognostic indicators in differentiated thyroid cancer JO - J Clin Endocrinol Metab. VL - 88 UR - https://doi.org/10.1210/jc.2002-021113 DO - 10.1210/jc.2002-021113 ID - Boelaert2003 ER - TY - JOUR AU - St Bernard, R. AU - Zheng, L. AU - Liu, W. AU - Winer, D. AU - Asa, S. L. AU - Ezzat, S. PY - 2005 DA - 2005// TI - Fibroblast growth factor receptors as molecular targets in thyroid carcinoma JO - Endocrinology. VL - 146 UR - https://doi.org/10.1210/en.2004-1134 DO - 10.1210/en.2004-1134 ID - St Bernard2005 ER - TY - JOUR AU - Kondo, T. AU - Zheng, L. AU - Liu, W. AU - Kurebayashi, J. AU - Asa, S. L. AU - Ezzat, S. PY - 2007 DA - 2007// TI - Epigenetically controlled fibroblast growth factor receptor 2 signaling imposes on the RAS/BRAF/mitogen-activated protein kinase pathway to modulate thyroid cancer progression JO - Cancer Res. VL - 67 UR - https://doi.org/10.1158/0008-5472.CAN-06-4477 DO - 10.1158/0008-5472.CAN-06-4477 ID - Kondo2007 ER - TY - JOUR AU - Giordano, T. J. AU - Kuick, R. AU - Thomas, D. G. AU - Misek, D. E. AU - Vinco, M. AU - Sanders, D. PY - 2005 DA - 2005// TI - Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis JO - Oncogene. VL - 24 UR - https://doi.org/10.1038/sj.onc.1208822 DO - 10.1038/sj.onc.1208822 ID - Giordano2005 ER - TY - JOUR AU - Lin, J. D. AU - Fu, S. S. AU - Chen, J. Y. AU - Lee, C. H. AU - Chau, W. K. AU - Cheng, C. W. PY - 2016 DA - 2016// TI - Clinical manifestations and gene expression in patients with conventional papillary thyroid carcinoma carrying the BRAF(V600E) mutation and BRAF pseudogene JO - Thyroid. VL - 26 UR - https://doi.org/10.1089/thy.2015.0044 DO - 10.1089/thy.2015.0044 ID - Lin2016 ER - TY - JOUR AU - Zhao, X. P. AU - Zhang, H. AU - Jiao, J. Y. AU - Tang, D. X. AU - Wu, Y. L. AU - Pan, C. B. PY - 2016 DA - 2016// TI - Overexpression of HMGA2 promotes tongue cancer metastasis through EMT pathway JO - J Transl Med. VL - 14 UR - https://doi.org/10.1186/s12967-016-1082-7 DO - 10.1186/s12967-016-1082-7 ID - Zhao2016 ER - TY - JOUR AU - Schulten, H. J. AU - Alotibi, R. AU - Al-Ahmadi, A. AU - Ata, M. AU - Karim, S. AU - Huwait, E. PY - 2015 DA - 2015// TI - Effect of BRAF mutational status on expression profiles in conventional papillary thyroid carcinomas JO - BMC Genomics VL - Suppl 1 UR - https://doi.org/10.1186/1471-2164-16-S1-S6 DO - 10.1186/1471-2164-16-S1-S6 ID - Schulten2015 ER - TY - JOUR AU - Scott, G. K. AU - Goga, A. AU - Bhaumik, D. AU - Berger, C. E. AU - Sullivan, C. S. AU - Benz, C. C. PY - 2007 DA - 2007// TI - Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b JO - J Biol Chem. VL - 282 UR - https://doi.org/10.1074/jbc.M609383200 DO - 10.1074/jbc.M609383200 ID - Scott2007 ER - TY - JOUR AU - Chiappetta, G. AU - Ferraro, A. AU - Vuttariello, E. AU - Monaco, M. AU - Galdiero, F. AU - Simone, V. PY - 2008 DA - 2008// TI - HMGA2 mRNA expression correlates with the malignant phenotype in human thyroid neoplasias JO - Eur J Cancer. VL - 44 UR - https://doi.org/10.1016/j.ejca.2008.02.039 DO - 10.1016/j.ejca.2008.02.039 ID - Chiappetta2008 ER - TY - JOUR AU - Tan, E. J. AU - Kahata, K. AU - Idås, O. AU - Thuault, S. AU - Heldin, C. H. AU - Moustakas, A. PY - 2015 DA - 2015// TI - The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition JO - Nucleic Acids Res. VL - 43 UR - https://doi.org/10.1093/nar/gku1293 DO - 10.1093/nar/gku1293 ID - Tan2015 ER - TY - JOUR AU - Fry, W. H. AU - Simion, C. AU - Sweeney, C. AU - Carraway, K. L. PY - 2011 DA - 2011// TI - Quantity control of the ErbB3 receptor tyrosine kinase at the endoplasmic reticulum JO - Mol Cell Biol. VL - 31 UR - https://doi.org/10.1128/MCB.05105-11 DO - 10.1128/MCB.05105-11 ID - Fry2011 ER - TY - JOUR AU - Abel, E. V. AU - Basile, K. J. AU - Kugel, C. H. AU - Witkiewicz, A. K. AU - Le, K. AU - Amaravadi, R. K. PY - 2013 DA - 2013// TI - Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3 JO - J Clin Invest. VL - 123 UR - https://doi.org/10.1172/JCI65780 DO - 10.1172/JCI65780 ID - Abel2013 ER - TY - JOUR AU - Montero-Conde, C. AU - Ruiz-Llorente, S. AU - Dominguez, J. M. AU - Knauf, J. A. AU - Viale, A. AU - Sherman, E. J. PY - 2013 DA - 2013// TI - Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas JO - Cancer discovery. VL - 3 UR - https://doi.org/10.1158/2159-8290.CD-12-0531 DO - 10.1158/2159-8290.CD-12-0531 ID - Montero-Conde2013 ER - TY - JOUR AU - Gala, K. AU - Chandarlapaty, S. PY - 2014 DA - 2014// TI - Molecular pathways: HER3 targeted therapy JO - Clin Cancer Res. VL - 20 UR - https://doi.org/10.1158/1078-0432.CCR-13-1549 DO - 10.1158/1078-0432.CCR-13-1549 ID - Gala2014 ER -