Table 3 Correlations between adiponectin plasma levels, gene expression, DNA methylation, and offspring clinical variables in the cohort as a whole (O-GDM, O-T1DM, and O-BP combined)

Adiponectin plasma levels

0.169 (0.032)

−0.084 (0.376)

ADIPOQ gene expression

0.169 (0.032)

−0.266 (0.013)

Average ADIPOQ DNA methylation

−0.084 (0.376)

−0.266 (0.013)

BMI (kg/m²)

−0.195 (0.005)

−0.417 (<0.001)

0.359 (<0.001) ^a

Fasting insulin (pmol/l)

−0.281 (<0.001)

−0.341 (<0.001)

0.318 (0.001) ^a

Fasting plasma glucose (mmol/l)

−0.145 (0.039)

−0.163 (0.039)

0.195 (0.038) ^a

120-min plasma glucose (mmol/l)

−0.141 (0.049)

−0.063 (0.441)

0.219 (0.022) ^a

Total body fat (%)

−0.078 (0.268)

−0.164 (0.038)

0.212 (0.024) ^a

HOMA-IR

−0.289 (<0.001)

−0.360 (<0.001)

0.344(<0.001) ^a

Mean systolic blood pressure (mmHg)

−0.195 (0.005)

−0.274 (<0.001)

0.175 (0.062)^a

Mean diastolic blood pressure (mmHg)

−0.139 (0.048)

−0.351 (<0.001)

0.148 (0.115)^a

Waist circumference (cm)

−0.239 (0.001)

−0.439 (<0.001)

0.447 (<0.001) ^a

HDL cholesterol (mmol/l)

0.240 (0.001)

0.356 (<0.001)

−0.286 (0.002) ^a