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Table 3 List of DMRs identified between total cortex and cerebellum

From: Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue

Start (bp) Stop (bp) Gene(s) p value
1 100 D-Loop -
101 200 D-Loop -
201 300 D-Loop -
301 400 D-Loop -
401 500 D-Loop 7.99E−03
501 600 MT-TF 4.49E−03
601 700 MT-TF/MT-RNR1 1.16E−02
701 800 MT-RNR1 3.22E−03
801 900 MT-RNR1 1.91E04
901 1000 MT-RNR1 ND
1001 1100 MT-RNR1 ND
1101 1200 MT-RNR1 ND
1201 1300 MT-RNR1 ND
1301 1400 MT-RNR1 ND
1401 1500 MT-RNR1 ND
1501 1600 MT-RNR1 ND
1601 1700 MT-RNR1/MT-TV/MT-RNR2 ND
1701 1800 MT-RNR2 ND
1801 1900 MT-RNR2 ND
1901 2000 MT-RNR2 ND
2001 2100 MT-RNR2 ND
2101 2200 MT-RNR2 ND
2201 2300 MT-RNR2 ND
2301 2400 MT-RNR2 8.10E−03
2401 2500 MT-RNR2 7.50E−03
2501 2600 MT-RNR2 5.14E−03
2601 2700 MT-RNR2 ND
2701 2800 MT-RNR2 ND
2801 2900 MT-RNR2 -
2901 3000 MT-RNR2 -
3001 3100 MT-RNR2 -
3101 3200 MT-RNR2 -
3201 3300 MT-RNR2/MT-TL 1.51E−03
3301 3400 MT-TL1/MT-ND1 -
3401 3500 MT-ND1 1.37E−02
3501 3600 MT-ND1 4.27E−03
3601 3700 MT-ND1 5.56E−03
3701 3800 MT-ND1 8.21E−03
3801 3900 MT-ND1 -
3901 4000 MT-ND1 -
4001 4100 MT-ND1 3.07E06
4101 4200 MT-ND1 -
4201 4300 MT-ND1/MT-TI ND
4301 4400 MT-TI/MT-TQ ND
4401 4500 MT-TM/MT-ND2 ND
4501 4600 MT-ND2 ND
4601 4700 MT-ND2 ND
4701 4800 MT-ND2 ND
4801 4900 MT-ND2 ND
4901 5000 MT-ND2 ND
5001 5100 MT-ND2 ND
5101 5200 MT-ND2 ND
5201 5300 MT-ND2 ND
5301 5400 MT-ND2 ND
5401 5500 MT-ND2 ND
5501 5600 MT-ND2/MT-TW/MT-TA ND
5601 5700 MT-TA/MT-TN ND
5701 5800 MT-TN/MT-TC ND
5801 5900 MT-TC/MT-TY ND
5901 6000 MT-CO1 ND
6001 6100 MT-CO1 ND
6101 6200 MT-CO1 ND
6201 6300 MT-CO1 ND
6301 6400 MT-CO1 ND
6401 6500 MT-CO1 ND
6501 6600 MT-CO1 ND
6601 6700 MT-CO1 ND
6701 6800 MT-CO1 ND
6801 6900 MT-CO1 ND
6901 7000 MT-CO1 ND
7001 7100 MT-CO1 ND
7101 7200 MT-CO1 ND
7201 7300 MT-CO1 ND
7301 7400 MT-CO1 ND
7401 7500 MT-CO1/MT-TS1 ND
7501 7600 MT-TS1/MT-TD/MT-CO2 ND
7601 7700 MT-CO2 ND
7701 7800 MT-CO2 ND
7801 7900 MT-CO2 ND
7901 8000 MT-CO2 ND
8001 8100 MT-CO2 ND
8101 8200 MT-CO2 ND
8201 8300 MT-CO2/MT-TK ND
8301 8400 MT-TK/MT-ATP8 ND
8401 8500 MT-ATP8 ND
8501 8600 MT-ATP8/MT-ATP6 ND
8601 8700 MT-ATP6 ND
8701 8800 MT-ATP6 ND
8801 8900 MT-ATP6 ND
8901 9000 MT-ATP6 ND
9001 9100 MT-ATP6 ND
9101 9200 MT-ATP6 ND
9201 9300 MT-ATP6/MT-CO3 ND
9301 9400 MT-CO3 ND
9401 9500 MT-CO3 ND
9501 9600 MT-CO3 ND
9601 9700 MT-CO3 ND
9701 9800 MT-CO3 ND
9801 9900 MT-CO3 -
9901 10000 MT-CO3/MT-TG -
10001 10100 MT-TG/MT-ND3 1.81E−02
10101 10200 MT-ND3 1.39E−02
10201 10300 MT-ND3 3.53E04
10301 10400 MT-ND3/MT-TR/MT-ND4L 1.19E05
10401 10500 MT-ND4L 2.61E04
10501 10600 MT-ND4L 9.05E−04
10601 10700 MT-ND4L ND
10701 10800 MT-ND4L/MT-ND4 ND
10801 10900 MT-ND4 ND
10901 11000 MT-ND4 ND
11001 11100 MT-ND4 ND
11101 11200 MT-ND4 ND
11201 11300 MT-ND4 8.86E05
11301 11400 MT-ND4 1.65E−03
11401 11500 MT-ND4 ND
11501 11600 MT-ND4 ND
11601 11700 MT-ND4 ND
11701 11800 MT-ND4 ND
11801 11900 MT-ND4 ND
11901 12000 MT-ND4 ND
12001 12100 MT-ND4 ND
12101 12200 MT-ND4/MT-TH ND
12201 12300 MT-TS2/MT-TL2 ND
12301 12400 MT-TL2/MT-ND5 -
12401 12500 MT-ND5 -
12501 12600 MT-ND5 -
12601 12700 MT-ND5 -
12701 12800 MT-ND5 1.81E−03
12801 12900 MT-ND5 1.05E−02
12901 13000 MT-ND5 8.23E−03
13001 13100 MT-ND5 ND
13101 13200 MT-ND5 ND
13201 13300 MT-ND5 ND
13301 13400 MT-ND5 1.44E−03
13401 13500 MT-ND5 9.13E−04
13501 13600 MT-ND5 1.61E−02
13601 13700 MT-ND5 3.89E−02
13701 13800 MT-ND5 2.77E04
13801 13900 MT-ND5 2.80E−03
13901 14000 MT-ND5 1.88E−02
14001 14100 MT-ND5 9.31E−03
14101 14200 MT-ND5/MT-ND6 -
14201 14300 MT-ND6 -
14301 14400 MT-ND6 1.04E−02
14401 14500 MT-ND6 1.99E−02
14501 14600 MT-ND6 2.26E−02
14601 14700 MT-ND6/MT-TE 3.82E−03
14701 14800 MT-TE/MT-CYB 1.92E−02
14801 14900 MT-CYB ND
14901 15000 MT-CYB ND
15001 15100 MT-CYB ND
15101 15200 MT-CYB 3.30E−02
15201 15300 MT-CYB -
15301 15400 MT-CYB -
15401 15500 MT-CYB 8.52E−04
15501 15600 MT-CYB 7.43E−04
15601 15700 MT-CYB 1.16E−02
15701 15800 MT-CYB 2.24E−02
15801 15900 MT-CYB/MT-TT -
15901 16000 MT-TT/MT-TP -
16001 16100 MT-TP -
16101 16200 D-Loop 2.23E−03
16201 16300 D-Loop 5.02E04
16301 16400 D-Loop 1.84E−03
16401 16500 D-Loop 1.12E−03
16501 16600 D-Loop 2.20E−03
  1. Shown is the location of the DMR within ChrM (based on GENCODE), the gene(s) residing within the 100 bp window, and p value from a multilevel mixed effects model. Results are displayed in order of genomic position. RPKM and corresponding p values are shown for windows if p < 0.05. Key: - denotes data not significant (p > 0.05); ND denotes not determined as the window was not included in analysis due to removal in NUMT pipeline; bold denotes windows that reached our Bonferroni significant threshold of p < 7.04E−04