Table 1 Population characteristics and anthropometric data for 48 pre-pubertal children examined at age 6–11 years stratified by PON1 Q192R genotype and prenatal pesticide exposure

N

11

13

12

12

Female sex

5 (45.5)

7 (53.8)

6 (50.0)

6 (50.0)

Maternal smoking in pregnancy

0 (0)

0 (0)

0 (0)

0 (0)

SES^a

7/4 (63.6/36.4)

3/10 (23.1/76.9)*

5/7 (41.7/58.3)

2/10 (16.7/83.3)

Birth weight (g)

3640 (2600; 5412)

3382 (2750; 4573)

3789 (2984; 4345)

3500 (2900; 3914)*

Gestational age (days)

276 (257; 291)

283 (265; 295)

283 (261; 298)

281 (266; 291)

Age (years)

7.6 (6.2; 9.8)

8.4 (6.7; 10,0)

7.8 (6.6; 9.5)

7.7 (7.1; 9.4)

Height (cm)

133.3 (117.3; 145.2)

130.3 (109.7; 139.2)

130.9 (113.7; 149.1)

128.6 (119.3; 142,5)

Weight (kg)

30.9 (18.7; 38.0)

28.3 (18.0; 30.7)

26.3 (19.9; 36.5)

27.4 (19.5; 37.8)

BMI (kg/m²)

16.2 (13.7; 20.5)

15.3 (14.9; 18.3)

15.5 (13.8; 16.9)

15.7 (13.8; 19.7)

BMI Z scores

0.66 (−1.03; 3.21)

−0.18 (−0.80; 1.49)

−0.04 (−1.31; 0.89)

−0.01 (−0.98; 3.14)

Delta BMI Z score since birth

−0.45 (−2.15; 2.97)

−0.71 (−2.57; 1.87)

−0.56 (−2.52; 1.03)

0.95 (−2.08; 2.97)*

Abdominal circumference (cm)

60.4 (52.0; 75.8)

58.7 (52.1; 66.8)

58.3 (52.0; 68.1)

60.8 (51.8; 70.6)*

Sum of four skin folds (mm)

38.4 (27.1; 85.4)

33.6 (25.4; 54.5)

34.0 (20.2; 45.2)

44.6 (28.8; 72.0)*

Systolic blood pressure (mmHg)

98.7 (93.7; 110.4)

97.2 (84.3; 105.3)

99.7 (84.7; 106.8)

101.7 (91.0; 108.6)

Diastolic blood pressure (mmHg)

54.7 (46.0; 69.9)

56.2 (46.0; 62.0)

56.3 (49.3; 69.1)

63.0 (57.3; 73.1)**

Leptin (ng/ml)

1.47 (0.70; 9.18)

4.40 (0.60; 15.29)

1.41 (0.67; 5.90)

4.69 (1.79; 12.25)**

Insulin (ng/ml)

0.36 (0.22; 1.15)

0.52 (0.23; 2.55)

0.34 (0.16; 1.62)

1.11 (0.24; 7.10)*

Paraoxonase activity (nmol/min/ml)

27.5 (9.9; 38.0)

30.9 (21.0; 38.9)

58.6 (41.9; 68.7)

59.6 (50.3; 71.5)