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Table 2 Top 10 differentially methylated CpG sites in smokers compared to non-smokers, sorted by P value

From: DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

CpG site

Gene symbol

Chromosome

aProbe Type

P value

bGene location of first annotated transcript

cIsland location

cg14531093

ANKRD9

14

I

4.04E-06

Body

Island

cg15011943

HLA-DRB5

6

II

2.16E-05

Body

S_Shelf

cg18620571

TNFAIP2

14

I

3.28E-05

Body

Island

cg22837763

ANGPT1

8

II

3.86E-05

Body

 

cg10154826

FAM8A1

6

II

4.26E-05

1st Exon

Island

cg17289692

 

3

II

5.48E-05

  

cg07753241

ATXN7;THOC7

3

II

6.74E-05

TSS1500

Island

cg01096617

CNOT1

16

II

7.50E-05

Body

 

cg25383568

ACTN4

19

I

9.46E-05

Body

Island

cg20377766

LOC387646

10

II

9.63E-05

TSS1500

Island

  1. aProbe type I or type II design specified on the assay
  2. bLocation relative to the first listed transcript
  3. cS_ denote the downstream end of the island region