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Table 1 General clinical characteristics of non-smokers, smokers, and COPD patients

From: DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

Parameters

Non-smokers

Smokers

COPD

Number of subjects

8

8

8

M:F ratio

6:2

7:1

5:3

Male:female (%)

(75%:25%)

(87.5%:12.5%)

(62.5%:37.5%)

Age, year

62.62 ± 1.87

61 ± 2.33

56.1 ± 2.57

(55–69)

(52–71)

(45–63)

Smoking, pack years

–

27.14 ± 5.96***

28.8 ± 4.32***

(10–50)a

(10–43)a

FEV1 % predicted

100.28 ± 5.55

88.75 ± 4.04

23 ± 4.41***; ###

(81–124)b

(68–102)

(10–43)

FEV1/FVC %

0.79 ± 0.01

0.81 ± 0.02

0.33 ± 0.03***; ###

(0.73–0.85)b

(0.75–0.95)

(0.25–0.5)

  1. aNo pack years details for one subject in the smokers and COPD groups
  2. bNo FEV1 % predicted (one subject) and FEV1/FVC % values (two subjects) in the non-smokers group
  3. *** P < 0.001 vs. non-smokers, ### P < 0.001 vs. smokers
  4. M:F Male to Female ratio, FEV 1 forced expiratory volume in 1 s