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Table 2 Comparison of REPLI-g and Infinium DNA restoration of FFPE samples analysed on the EPIC array

From: Validation of the MethylationEPIC BeadChip for fresh-frozen and formalin-fixed paraffin-embedded tumours

Sample FF vs FFPE REPLI-g (r) FF vs FFPE Infinium (r)
T01 0.902 0.920
T06 0.931 0.902
T08 0.962 0.950
T09 0.987 0.987
Mean 0.946 0.940
  1. Pearson correlation for β values from four formalin-fixed paraffin-embedded (FFPE) paediatric brain tumour samples, restored with REPLI-g and Infinium, compared with paired fresh-frozen (FF) samples processed on the EPIC array (p < 2.2 · 10−16 for all sample pairs)