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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Validation of the MethylationEPIC BeadChip for fresh-frozen and formalin-fixed paraffin-embedded tumours

Fig. 1

Experimental setup. a Nine fresh-frozen (FF) paediatric brain tumour samples (tumours T01-T09) were processed on the Illumina 450K and EPIC array to compare the platforms. Nine formalin-fixed paraffin-embedded (FFPE) samples paired to the FF samples were analysed on the EPIC array to assess the correlation between FF and FFPE and thereby the suitability of the array in a clinical setting (FFPE samples). Four of the FFPE samples (tumours T01, T06, T08, T09) were restored with both the REPLI-g and Infinium protocol to enable comparison between the methods. b Three FFPE samples (tumours T10-T12), restored with REPLI-g, were analysed with the 450K as well as the EPIC array to compare the platforms for FFPE samples

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Clinical Epigenetics

ISSN: 1868-7083

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