TY - JOUR AU - Luger, K. AU - Mader, A. W. AU - Richmond, R. K. AU - Sargent, D. F. AU - Richmond, T. J. PY - 1997 DA - 1997// TI - Crystal structure of the nucleosome core particle at 2.8 A resolution JO - Nature VL - 389 UR - https://doi.org/10.1038/38444 DO - 10.1038/38444 ID - Luger1997 ER - TY - JOUR AU - Bannister, A. J. AU - Kouzarides, T. PY - 2011 DA - 2011// TI - Regulation of chromatin by histone modifications JO - Cell Res VL - 21 UR - https://doi.org/10.1038/cr.2011.22 DO - 10.1038/cr.2011.22 ID - Bannister2011 ER - TY - JOUR AU - Fraga, M. F. AU - Ballestar, E. AU - Villar-Garea, A. AU - Boix-Chornet, M. AU - Espada, J. AU - Schotta, G. PY - 2005 DA - 2005// TI - Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer JO - Nat Genet VL - 37 UR - https://doi.org/10.1038/ng1531 DO - 10.1038/ng1531 ID - Fraga2005 ER - TY - JOUR AU - Elsheikh, S. E. AU - Green, A. R. AU - Rakha, E. A. AU - Powe, D. G. AU - Ahmed, R. A. AU - Collins, H. M. PY - 2009 DA - 2009// TI - Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome JO - Cancer Res VL - 69 UR - https://doi.org/10.1158/0008-5472.CAN-08-3907 DO - 10.1158/0008-5472.CAN-08-3907 ID - Elsheikh2009 ER - TY - JOUR AU - Seligson, D. B. AU - Horvath, S. AU - Shi, T. AU - Yu, H. AU - Tze, S. AU - Grunstein, M. PY - 2005 DA - 2005// TI - Global histone modification patterns predict risk of prostate cancer recurrence JO - Nature VL - 435 UR - https://doi.org/10.1038/nature03672 DO - 10.1038/nature03672 ID - Seligson2005 ER - TY - JOUR AU - Holdenrieder, S. AU - Nagel, D. AU - Schalhorn, A. AU - Heinemann, V. AU - Wilkowski, R. AU - Pawel, J. PY - 2008 DA - 2008// TI - Clinical relevance of circulating nucleosomes in cancer JO - Ann N Y Acad Sci VL - 1137 UR - https://doi.org/10.1196/annals.1448.012 DO - 10.1196/annals.1448.012 ID - Holdenrieder2008 ER - TY - JOUR AU - Karachaliou, N. AU - Mayo-De-Las-Casas, C. AU - Molina-Vila, M. A. AU - Rosell, R. PY - 2015 DA - 2015// TI - Real-time liquid biopsies become a reality in cancer treatment JO - Ann Transl Med VL - 3 ID - Karachaliou2015 ER - TY - JOUR AU - Chen, R. AU - Kang, R. AU - Fan, X. -. G. AU - Tang, D. PY - 2014 DA - 2014// TI - Release and activity of histone in diseases JO - Cell Death Dis VL - 5 UR - https://doi.org/10.1038/cddis.2014.337 DO - 10.1038/cddis.2014.337 ID - Chen2014 ER - TY - JOUR AU - Stroun, M. AU - Maurice, P. AU - Vasioukhin, V. AU - Lyautey, J. AU - Lederrey, C. AU - Lefort, F. PY - 2000 DA - 2000// TI - The origin and mechanism of circulating DNA JO - Ann N Y Acad Sci VL - 906 UR - https://doi.org/10.1111/j.1749-6632.2000.tb06608.x DO - 10.1111/j.1749-6632.2000.tb06608.x ID - Stroun2000 ER - TY - JOUR AU - Holdenrieder, S. AU - Stieber, P. AU - Bodenmüller, H. AU - Busch, M. AU - Fertig, G. AU - Fürst, H. PY - 2001 DA - 2001// TI - Nucleosomes in serum of patients with benign and malignant diseases JO - Int J Cancer VL - 95 UR - https://doi.org/3.0.CO;2-Q DO - 3.0.CO;2-Q ID - Holdenrieder2001 ER - TY - JOUR AU - Shapiro, B. AU - Chakrabarty, M. AU - Cohn, E. M. AU - Leon, S. A. PY - 1983 DA - 1983// TI - Determination of circulating DNA levels in patients with benign or malignant gastrointestinal disease JO - Cancer VL - 51 UR - https://doi.org/3.0.CO;2-S DO - 3.0.CO;2-S ID - Shapiro1983 ER - TY - JOUR AU - Holdenrieder, S. AU - Stieber, P. AU - Pawel, J. AU - Raith, H. AU - Nagel, D. AU - Feldmann, K. PY - 2004 DA - 2004// TI - Circulating nucleosomes predict the response to chemotherapy in patients with advanced non–small cell lung cancer JO - Am Assoc Cancer Res VL - 10 ID - Holdenrieder2004 ER - TY - JOUR AU - Holdenrieder, S. AU - Dharuman, Y. AU - Standop, J. AU - Trimpop, N. AU - Herzog, M. AU - Hettwer, K. PY - 2014 DA - 2014// TI - Novel serum nucleosomics biomarkers for the detection of colorectal cancer JO - Anticancer Res VL - 34 ID - Holdenrieder2014 ER - TY - JOUR AU - Deligezer, U. AU - Akisik, E. E. AU - Erten, N. AU - Dalay, N. PY - 2008 DA - 2008// TI - Sequence-specific histone methylation is detectable on circulating nucleosomes in plasma JO - Clin Chem VL - 54 UR - https://doi.org/10.1373/clinchem.2007.101766 DO - 10.1373/clinchem.2007.101766 ID - Deligezer2008 ER - TY - JOUR AU - Leszinski, G. AU - Gezer, U. AU - Siegele, B. AU - Stoetzer, O. AU - Holdenrieder, S. PY - 2012 DA - 2012// TI - Relevance of histone marks H3K9me3 and H4K20me3 in cancer JO - Anticancer Res VL - 32 ID - Leszinski2012 ER - TY - JOUR AU - Khare, S. P. AU - Sharma, A. AU - Deodhar, K. K. AU - Gupta, S. PY - 2011 DA - 2011// TI - Overexpression of histone variant H2A.1 and cellular transformation are related in N-nitrosodiethylamine-induced sequential hepatocarcinogenesis JO - Exp Biol Med (Maywood) VL - 236 UR - https://doi.org/10.1258/ebm.2010.010140 DO - 10.1258/ebm.2010.010140 ID - Khare2011 ER - TY - STD TI - Parasuraman S, Raveendran R, Kesavan R. Blood sample collection in small laboratory animals. J Pharmacol Pharmacother. 2010;1:87–93. ID - ref17 ER - TY - STD TI - Ryan CA, Annunziato AT. Separation of histone variants and post-translationally modified isoforms by triton/acetic acid/urea polyacrylamide gel electrophoresis. Curr Protoc Mol Biol. 2001. May; Chapter 21:Unit 21.2. doi:10.1002/0471142727.mb2102s45. ID - ref18 ER - TY - JOUR AU - Chevallet, M. AU - Luche, S. AU - Rabilloud, T. PY - 2006 DA - 2006// TI - Silver staining of proteins in polyacrylamide gels JO - Nat Protoc VL - 1 UR - https://doi.org/10.1038/nprot.2006.288 DO - 10.1038/nprot.2006.288 ID - Chevallet2006 ER - TY - JOUR AU - Yu, Y. -. Q. AU - Gilar, M. AU - Lee, P. J. AU - Bouvier, E. S. P. AU - Gebler, J. C. PY - 2003 DA - 2003// TI - Enzyme-friendly, mass spectrometry-compatible surfactant for in-solution enzymatic digestion of proteins JO - Anal Chem VL - 75 UR - https://doi.org/10.1021/ac0346196 DO - 10.1021/ac0346196 ID - Yu2003 ER - TY - JOUR AU - Bonner, W. M. AU - Redon, C. E. AU - Dickey, J. S. AU - Nakamura, A. J. AU - Olga, A. AU - Solier, S. PY - 2011 DA - 2011// TI - GammaH2AX and cancer JO - Nat Rev Cancer VL - 8 UR - https://doi.org/10.1038/nrc2523 DO - 10.1038/nrc2523 ID - Bonner2011 ER - TY - STD TI - Khan SA, Amnekar R, Khade B, Barreto SG, Ramadwar M, Shrikhande S V, et al. of histone H3 serine 10 phosphorylation defines distance-dependent prognostic value of negative resection margin in gastric cancer. Clin Epigenetics. 2016;8(1):88. ID - ref22 ER - TY - STD TI - Wang L, Zou X, Berger AD, Twiss C, Peng Y, Li Y, et al. Increased expression of histone deacetylaces (HDACs) and inhibition of prostate cancer growth and invasion by HDAC inhibitor SAHA. Am J Transl Res. 2009;1(1):62–71. ID - ref23 ER - TY - STD TI - Cohen I, Schneider R. Histone modifiers in cancer: friends or foes? Genes Cancer. 2011;2(6):631–647. ID - ref24 ER - TY - JOUR AU - Holdenrieder, S. AU - Stieber, P. AU - Bodenmuller, H. AU - Busch, M. AU - Pawel, J. AU - Schalhorn, A. PY - 2001 DA - 2001// TI - Circulating nucleosomes in serum JO - Ann N Y Acad Sci VL - 945 UR - https://doi.org/10.1111/j.1749-6632.2001.tb03869.x DO - 10.1111/j.1749-6632.2001.tb03869.x ID - Holdenrieder2001 ER - TY - JOUR AU - Khan, S. A. AU - Reddy, D. AU - Gupta, S. PY - 2015 DA - 2015// TI - Global histone post-translationl modifications and cancer: biomarkers for diagnosis, prognosis and treatment? JO - World J of Biol Chem VL - 6 UR - https://doi.org/10.4331/wjbc.v6.i4.333 DO - 10.4331/wjbc.v6.i4.333 ID - Khan2015 ER - TY - JOUR AU - Rigby, L. AU - Muscat, A. AU - Ashley, D. AU - Algar, E. PY - 2012 DA - 2012// TI - Methods for the analysis of histone H3 and H4 acetylation in blood JO - Epigenetics VL - 7 UR - https://doi.org/10.4161/epi.20983 DO - 10.4161/epi.20983 ID - Rigby2012 ER - TY - JOUR AU - Glozak, M. A. AU - Seto, E. PY - 2007 DA - 2007// TI - Histone deacetylases and cancer JO - Oncogene VL - 26 UR - https://doi.org/10.1038/sj.onc.1210610 DO - 10.1038/sj.onc.1210610 ID - Glozak2007 ER - TY - JOUR AU - Liu, X. AU - Valentine, S. J. AU - Plasencia, M. D. PY - 2007 DA - 2007// TI - Mapping the human plasma proteome by SCX-LC-IMS-MS JO - J Am Soc Mass Spectrom VL - 18 UR - https://doi.org/10.1016/j.jasms.2007.04.012 DO - 10.1016/j.jasms.2007.04.012 ID - Liu2007 ER - TY - JOUR AU - Sennels, L. AU - Salek, M. AU - Lomas, L. AU - Boschetti, E. AU - Righetti, P. G. AU - Rappsilber, J. PY - 2007 DA - 2007// TI - Proteomic analysis of human blood serum using peptide library beads JO - J Proteome Res VL - 6 UR - https://doi.org/10.1021/pr070339l DO - 10.1021/pr070339l ID - Sennels2007 ER - TY - JOUR AU - Qiu, T. AU - Zhou, L. AU - Zhu, W. AU - Wang, T. AU - Wang, J. AU - Shu, Y. PY - 2013 DA - 2013// TI - Effects of treatment with histone deacetylase inhibitors in solid tumors: a review based on 30 clinical trials JO - Futur Oncol VL - 9 UR - https://doi.org/10.2217/fon.12.173 DO - 10.2217/fon.12.173 ID - Qiu2013 ER - TY - JOUR AU - Wagner, J. M. AU - Hackanson, B. AU - Lübbert, M. AU - Jung, M. PY - 2010 DA - 2010// TI - Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy JO - Clin Epigenetics VL - 1 UR - https://doi.org/10.1007/s13148-010-0012-4 DO - 10.1007/s13148-010-0012-4 ID - Wagner2010 ER - TY - JOUR AU - Gryder, B. E. AU - Sodji, Q. H. AU - Oyelere, A. K. PY - 2012 DA - 2012// TI - Targeted cancer therapy: giving histone deacetylase inhibitors all they need to succeed JO - Future Med Chem VL - 4 UR - https://doi.org/10.4155/fmc.12.3 DO - 10.4155/fmc.12.3 ID - Gryder2012 ER -