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Fig. 2 | Clinical Epigenetics

Fig. 2

From: PITX3 DNA methylation is an independent predictor of overall survival in patients with head and neck squamous cell carcinoma

Fig. 2

PITX3 DNA methylation in HNSCC specimens. Frequency of PITX3 DNA methylation in the training cohort (a) comprising 326 HNSCC patients and validation cohort (b) including 528 HNSCC patients. Shown are the methylation levels in tumor tissue only. PITX3 DNA methylation in tumor tissue compared to normal adjacent tissue from the training (c) and the validation (d) cohort, respectively. Tumor tissue was methylated significantly higher compared to corresponding normal adjacent tissue. p values refer to Wilcoxon-Mann-Whitney test

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