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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Genome-wide DNA methylation profile identified a unique set of differentially methylated immune genes in oral squamous cell carcinoma patients in India

Fig. 2

Validation of HumanMethylation450K bead chip data. The upper panel shows the avergae β values, and the lower panel shows the clonal validation by sequencing the bisulfite-converted products of a LXN and b PTPN22 promoters. The filled circle in the lower panel represents the methylated, and the open circle represents the unmethylated CpGs. Gene expression of c LXN and d PTPN22 showed significant differential expression between OSCC and adjacent normal tissues, correlating with methylation status

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