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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Improved results of LINE-1 methylation analysis in formalin-fixed, paraffin-embedded tissues with the application of a heating step during the DNA extraction process

Fig. 2

Mean methylation levels of the four LINE-1 CpG sites for xenograft tissue samples (n = 10) with five different durations of formalin fixation. DNA samples were heat-untreated (a) and heat-untreated (b). Both the paired Student’s t test and the paired Wilcoxon signed-rank test were performed to compare the mean methylation values of the four CpG sites between paired fresh-frozen and formalin-fixed, paraffin-embedded tissue samples. P values in the bar graph represent the values of both the parametric and the non-parametric tests

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Clinical Epigenetics

ISSN: 1868-7083

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