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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression

Fig. 2

Nuclear localization of 5caC and 5hmC in ependymoma cell lines. a 2.5XD 5caC and 5hmC signal intensity plots of the nuclei of two DKFZ-EP1NS cells with different levels of 5caC staining and a representative BXD-1425EPN nucleus compared with 2.5XD 5caC/5hmC signal intensity plot of a representative nucleus of a 13.5 dpc mouse brain cell. Merged views and individual channels are shown. be Merged views of the confocal images of 5caC and 5hmC immunostaining in representative nuclei of DKFZ-EP1NS and BXD-1425EPN cells (b, d) with arrows designating nuclear regions used for generation of the signal intensity profiles shown in c and e

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