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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression

Fig. 1

Paediatric medulloblastoma and ependymoma cell lines exhibit immunochemically detectable levels of 5hmC and 5caC. a, b Co-detection of 5caC with DAPI (a) and 5hmC (b) in HeLa cells and indicated paediatric brain tumour cell lines. Merged views and individual channels are shown. The cell cultures were stained in parallel at the same experimental conditions and were imaged at identical settings. c Co-immunostaining of 5hmC and 5caC in two representative DKFZ-EP1NS cells with different levels of 5caC signal (designated as detectable for the top nucleus and undetectable for the bottom nucleus) used for the categorization of 5caC staining presented in d. d Proportions of DKFZ-EP1NS cells with detectable or undetectable levels of 5caC and 5hmC signal

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