Skip to main content

Table 1 Demographic and relevant clinical features of CF patients and controls

From: DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis

  Discovery set (METHYLCF) Replication set (FrGMC)
C (n = 24) CF (n = 48) Mild (n = 23) Intermediary (n = 13) Severe (n = 12) CF (n = 30) Mild (n = 18) Severe (n = 12)
Age, yeara 37 26 34 25.5 22 24.5 27.0 23.5
Sex, M:F 13:11 32:16 17:6 11:2 4:8 19:11 14:4 5:7
BMI (kg/m2)a   20.9 22.1 20.5 19.8 19.9 21.4 18.0
Weight (kg)a   60.0 62.0 60.0 52.0 56.0 60.0 45.5
Height (cm)a   170 170 171 168 168.0 170.0 161.5
FEV1%a   48.0 64.8 48.0 41.5 91.0 102.0 24.0
FVC %a   74.0 87.0 67.0 66.5 98.5 105.0 46.0
% PI   100 100 100 100    
% Diabetes   36.7 47.8 23.0 33.3    
% Atopy   28.3 31.8 23.1 27.3    
% P. Aeruginosa   93.9 91.3 100 90.9    
% MRSA   34.1 22.7 30.8 60.0    
% Aspergillus   18.2 26.1 14.3 20.0    
  1. PI pancreatic insufficiency
  2. aMedian