DNA methylation at EDNRA in blood samples.
a The dot plots represent the mean DNA methylation of EDNRA in CF patients compared with controls (Wilcoxon p = 0.017). b DNA methylation at EDNRA correlated with pulmonary severity (Kruskal-Wallis p = 0.028). The horizontal line indicates the median in each group. c The heat map represents DNA methylation at 21 CpG dinucleotides. CFM mild CF patient, CFI intermediary CF patient, CFS severe CF patient