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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Increased Set1 binding at the promoter induces aberrant epigenetic alterations and up-regulates cyclic adenosine 5'-monophosphate response element modulator alpha in systemic lupus erythematosus

Fig. 2

H3K4me3 enrichment at the CREMα promoter in SLE and control CD4+ T cells. a Relative H3K4me3 enrichment within the CREMα promoter in SLE and healthy CD4+ T cells was assessed by ChIP and real-time PCR. Results were normalized to input DNA (total chromatin). b Positive correlation between the levels of H3K4me3 and CREMα mRNA in SLE CD4+ T cells. All reactions were run in triplicate

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