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Table 1 Clinical and biochemical characteristics of the study subjects

From: Augmentation of histone deacetylase 3 (HDAC3) epigenetic signature at the interface of proinflammation and insulin resistance in patients with type 2 diabetes

Parameter

Normal glucose tolerance (NGT) (n = 25)

Type 2 diabetes mellitus (T2DM) patients (n = 25)

p value*

Age (years)

45.2 ± 9

45.0 ± 9

0.928

Gender–male (female)

14 (11)

16 (9)

–

Body mass index (kg/m2)

25.5 ± 3.5

26.6 ± 4.3

0.318

Waist circumference (cm)

94 ± 7

93 ± 11

0.964

Fasting plasma glucose (mg/dl)

94 ± 11

189 ± 46

<0.001*

Glycated hemoglobin—HbA1c (%)

5.9 ± 0.4

9.2 ± 1.7

<0.001*

HOMA-IR

2.09 ± 1

4.4 ± 1.6

<0.001*

Systolic blood pressure (mmHg)

123 ± 10

135 ± 21

<0.05*

Diastolic blood pressure (mmHg)

79 ± 8

81 ± 11

0.426

Total cholesterol (mg/dl)

171 ± 32

170 ± 48

0.953

Serum triglycerides (mg/dl)

122 ± 52

140 ± 69

0.285

HDL cholesterol (mg/dl)

41 ± 9

40 ± 8

0.389

LDL cholesterol (mg/dl)

108 ± 31

103 ± 37

0.624

  1. Data represented as mean ± standard deviation (SD). Italic values are to indicate the statistical significance
  2. *p value for comparison between NGT and T2DM individuals