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Table 3 Univariate and multivariate Cox’s regression analysis of SOX21-AS1 expression for disease-specific survival and disease-free survival of OSCC patients

From: Aberrant DNA hypermethylation-silenced SOX21-AS1 gene expression and its clinical importance in oral cancer

Variable Number (%) Number of events Univariate analysis Multivariate analysis
Hazard ratio 95% CI P value Hazard ratio 95% CI P valuea
Disease-specific survival
SOX21-AS1
 High 57 (66.3) 8 1.00    1.00   
 Low 29 (33.7) 10 3.07 1.21–7.78 0.018 5.66 1.85–17.30 0.002
Disease-free survival
SOX21-AS1
 High 57 (66.3) 16 1.00    1.00   
 Low 29 (33.7) 10 1.60 0.72–3.54 0.249 2.96 1.14–7.64 0.025
  1. The italic indicated p value <0.05
  2. a P values were estimated by multiple Cox’s regression, in which adjusted for cell differentiation (moderate and poor vs well), AJCC pathological stage (stages III and IV vs stages I and II), and SOX21 (high vs low)