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Table 2 Collagen XVII α1 expression in normal cervix and cervical tumor tissues

From: In epithelial cancers, aberrant COL17A1 promoter methylation predicts its misexpression and increased invasion

Tissue

Total number of samples

Positive (%)

p value vs normala,b

Moderate or strong (%)

p value vs normala,b

Strong (%)

p value vs normala,b

Normal cervix

31

21 (68)

 

7 (23)

 

0 (0)

 

Squamous cell carcinoma

331

273 (82)

0.0442

146 (44)

0.0146

65 (20)

0.0016

Adenocarcinoma

27

19 (70)

0.5283

5 (19)

0.4769

0 (0)

1.0000

Adenosquamous carcinoma

3

2 (67)

0.7040

2 (67)

0.1644

1 (33)

0.0882

  1. aCalculated by Fisher’s exact test
  2. b p values in italic font remain statistically significant after accounting for multiple testing using a false discovery rate (FDR) of 5% [40]