Fig. 1

Reduced COL17A1 expression correlates with poor breast cancer patient prognosis. a Fold change in normalized COL4A1, COL4A2 (4A2), and COL17A1 (17A1) expression using 28 combined previously published datasets. p values: t test. b Fold change in normalized COL17A1 expression using the TCGA breast cancer RNAseq dataset. p value: Mann-Whitney U test. c–e Distant metastasis-free survival (c), recurrence-free survival (d), and overall survival (e) for breast cancer patients whose tumors express high (green) or low (red) COL17A1 levels. Patients were split in low and high expression groups using the median expression level as the cut-off [23]. p values: log-rank test. p value summaries: n/s not significant; ****p < 0.0001