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Table 3 List of HDACs and their current status in clinical trials

From: The quest for an effective and safe personalized cell therapy using epigenetic tools

Group Example Current status
Short-chain fatty acid Valproic acid Phase II CT
Phenyl butyrate Phase II CT
Pivanex Phase II CT
Hydroxamic acids Vorinostat FDA approved
Panobinostat Phase III CT
Belinostat Phase II CT
Abexinostat Phase II CT
Resminostat Phase II CT
Givinostat Phase II CT
Dacinostat Phase II CT
Pracinostat Phase II CT
Cyclic tetrapeptide Romidepsin FDA approved
Apicidin Phase II CT
Trapoxin A No data
Benzamide Mocetinostat Phase II CT
Entinostat Phase II CT
Rocilinostat Phase II CT