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Table 1 Significant aDMPs with a direct effect on aging (n = 26)

From: Intra-individual changes in DNA methylation not mediated by cell-type composition are correlated with aging during childhood

Chr Position Adjusted p value Mean difference 2 to 10 years Mean difference 10 to 16 years Mean difference 2 to 16 years Gene In CGI
1 69596098 0.0066 −0.0245 −0.0697 −0.0941 No
1 156883344a 0.0001 0.3168 0.0722 0.3891 PEAR1 No
1 156883372a 0.0463 0.1817 0.0111 0.1928 PEAR1 No
1 228400131 0.0263 0.2586 0.1004 0.3590 OBSNC Yes
1 228400135 0.0401 0.1595 0.0644 0.2239 OBSNC Yes
1 228400157 0.0463 0.2250 0.0287 0.2537 OBSNC Yes
1 228400210 0.0271 0.1841 0.0520 0.2361 OBSNC Yes
1 228400285 0.0427 0.2845 0.1512 0.4356 OBSNC Yes
2 233251546 0.0263 0.3498 0.0427 0.3926 ECEL1P2 Yes
2 233251551 0.0097 0.3378 0.0274 0.3652 ECEL1P2 Yes
4 117279915 0.0066 −0.1557 −0.1123 −0.2681 No
4 117280012 0.0284 −0.2395 −0.0671 −0.3066 No
5 78985800a 0.0455 0.1730 0.1003 0.2732 CMYA5 No
6 158097037 0.0409 0.2276 0.0110 0.2386 No
7 100463812a 0.0254 −0.3432 −0.0831 −0.4262 TRIP6 Yes
8 6656321 0.0090 −0.1563 −0.0884 −0.2447 No
9 136474402 0.0263 0.0524 0.0942 0.1466 Yes
9 140173334 0.0066 0.2576 0.0925 0.3501 C9orf167 Yes
9 140173378 0.0229 0.0922 0.0555 0.1477 C9orf167 Yes
10 129537308 0.0066 0.3634 0.0584 0.4218 FOX12 Yes
14 105881000 0.0263 0.0370 0.0214 0.0584 No
17 1179934 0.0344 −0.1037 −0.1406 −0.2443 TUSC5 No
17 75421287 0.0463 0.0196 0.0271 0.0467 SEPT9 No
17 76355061a 0.0066 0.2076 0.1098 0.3174 SOCS3 Yes
17 78262132 0.0486 0.1670 0.0400 0.2069 RNF213 No
20 62679572a 0.0401 0.1111 0.0882 0.1993 SOX18 Yes
  1. aReplicated CpG site