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Table 4 The expression of 3 miRNAs in sputum of a training set of stage I NSCLC patients and smokers with benign pulmonary nodules

From: Integrating DNA methylation and microRNA biomarkers in sputum for lung cancer detection

miRNAs AUC (95 % CI) Sensitivity (95 % CI) Specificity (95 % CI) P value
miR-31 0.76 (0.70 to 0.83) 61.66 (55.35 to 67.68) 81.86 (76.23 to 86.83) <0.001
miR-21 0.80 (0.72 to 0.86) 79.47 (72.38 to 82.94) 70.98 (65.48 to 77.46) <0.001
miR-210 0.84 (0.78 to 0.90) 76.58 (68.35 to 80.13) 81.16 (75–23.37 to 86.18) <0.001
Combined use of 3 miRNAs 0.89 (0.85 to 0.94) 81.48 (68.5 to 90.75) 85.91 (72.41 to 94.25) <0.001
  1. Abbreviations: AUC the area under receiver operating characteristic curve, CI confidence interval