From: Integrating DNA methylation and microRNA biomarkers in sputum for lung cancer detection
 | NSCLC cases (n = 144) | Controls (n = 171) | P value |
---|---|---|---|
Age | 66.32 (SD 12.68) | 65.23 (SD 10.15) | 0.33 |
Sex | Â | Â | 0.39 |
 Male | 114 | 135 |  |
 Female | 30 | 36 |  |
Pack-years | 44.38 (range, 6–169) | 43.26 (range, 5–119) | 0.35 |
FEV1/FVC | 0.47–0.53 | 0.43–0.84 | 0.08 |
Nodule size (cm) | 3.26 (SD, 1.38) | 2.17 (SD, 0.98) | <0.01 |
Stage, all are stage I | Â | Â | Â |
Histological type | Â | Â | Â |
Adenocarcinoma (AC) | 78 | Â | Â |
Squamous cell carcinoma (SCC) | 66 | Â | Â |