From: Integrating DNA methylation and microRNA biomarkers in sputum for lung cancer detection
 | NSCLC cases (n = 117) | Controls (n = 174) | P value |
---|---|---|---|
Age | 66.53 (SD 10.98) | 65.36 (SD 10.15) | 0.34 |
Sex | Â | Â | 0.36 |
 Male | 93 | 138 |  |
 Female | 24 | 36 |  |
Pack-years | 45.83 (range, 6–148) | 44.67 (range, 5–115) | 0.34 |
FEV1/FVC | 0.48–0.73 | 0.44–0.67 | 0.12 |
Nodule size (cm) | 3.23 (SD, 1.62) | 2.25 (SD, 1.04) | <0.01 |
Stage, all are stage I | Â | Â | Â |
Histological type | Â | Â | Â |
Adenocarcinoma (AC) | 63 | Â | Â |
Squamous cell carcinoma (SCC) | 54 | Â | Â |