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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Global DNA methylation profiling reveals new insights into epigenetically deregulated protein coding and long noncoding RNAs in CLL

Fig. 5

CLL-associated differentially methylated repeat elements (DMrE) over normal sorted B cell. a The heatplot represents the enrichment of cllDMRs over different repeat elements in B cell comparison. b Validation of IGHV-mutated specific hypermethylated SINE-ALU repeat region in 70 CLL patient samples and 8 normal B cell controls using pyrosequencing method. Statistical significance was derived using unpaired Student’s t test, *p < 0.05, **p < 0.01, and ***p < 0.001

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