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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Global DNA methylation patterns in Barrett’s esophagus, dysplastic Barrett’s, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco use

Fig. 6

Selected genes containing differentially methylated regions (DMR) when comparing smoker and nonsmoker cases, depicting the location of multiple contiguous differentially methylated CpG sites. Each panel contains the gene name and chromosomal location, alternate transcripts, exons and introns (large and small orange boxes), location of CpG islands (green boxes), DML (blue and pink dots), and the DMR (yellow box). Smokers are shown in pink and nonsmokers in blue. a TNXB gene, BE cases. b HOXA4 gene, BE cases. c GFI1, HGD/EAC cases. d CLDN11 gene, HGD/EAC cases

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Clinical Epigenetics

ISSN: 1868-7083

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