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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Global DNA methylation patterns in Barrett’s esophagus, dysplastic Barrett’s, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco use

Fig. 3

Selected genes containing differentially methylated regions (DMR) when comparing tissue samples from subjects with high vs. low BMI. The presence of concordant aberrant methylation is seen in the contiguous CpG sites in these DMR. Each panel contains the gene name and chromosomal location, alternate transcripts, exons and introns (large and small orange boxes), location of CpG islands (green boxes), DML (blue and pink dots), and the DMR (yellow box). Cases with BMI ≥30 are shown in pink and BMI < 30 in blue. a TFAP2C gene, BE cases. b DIP2C gene, BE cases. c ZNF790, HGD/EAC cases. d SIM2 gene, HGD/EAC cases

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Clinical Epigenetics

ISSN: 1868-7083

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