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Table 2 Top 30 CpGs differentially methylated in blood DNA in relation to current smoking compared to never smoking (FDR < 0.05, ordered by chromosomal location)

From: DNA methylation and smoking in Korean adults: epigenome-wide association study

Chra

Gene

Distance to geneb

Probe

Positionc

Coefd

SEe

P f

2

CCDC104

 

cg21597209

55746709

−0.009

0.002

6.2E−07

DGUOK

 

cg19394739

74154363

−0.012

0.002

3.5E−07

CLASP1

 

cg22346073

122402890

−0.056

0.010

5.1E−08

SATB2

 

cg21136715

200322252

−0.035

0.006

2.1E−07

ALPPL2

12,850

cg05951221g

233284402

−0.088

0.014

8.4E−09

3

GPR15

 

cg19859270g

98251294

−0.027

0.005

1.0E−07

5

AHRR

 

cg05575921g

373378

−0.203

0.025

6.5E−13

 

cg25648203g

395444

−0.079

0.015

6.2E−07

LINC01019

−239,389

cg11405538

3177877

0.124

0.022

1.3E−07

SOX30

 

cg06995810

157079468

0.048

0.009

1.0E−06

7

TSPAN13

 

cg05848863

16794078

−0.024

0.004

3.6E−07

PLEKHA8

 

cg09762120

30108301

0.040

0.007

2.8E−08

ADCYAP1R1

 

cg20165074

31091813

−0.008

0.002

6.7E−07

10

FAM53B

 

cg20723792

126360669

−0.097

0.014

4.8E−10

11

IRF7

 

cg27271532

612762

−0.035

0.006

3.8E−07

E2F8

 

cg15604507

19263433

−0.021

0.004

5.7E−07

CCND1

 

cg09520904

69462943

−0.036

0.007

7.5E−07

DIXDC1

 

cg11471799

111807548

−0.023

0.004

6.2E−07

12

CDK2AP1

 

cg13421247

123756945

−0.058

0.011

9.8E−07

14

CFL2

−44,147

cg23429457

35135441

−0.040

0.007

2.0E−07

EXOC3L4

−20,369

cg04884342

103546112

0.020

0.004

5.6E−07

15

CALML4

 

cg00388154

68498857

−0.058

0.011

2.9E−07

CORO2B

 

cg18765659

69018349

−0.053

0.010

7.4E−07

TLE3

 

cg06730438h

70355664

−0.016

0.003

4.9E−07

16

ALDOA

 

cg24780263

30064201

−0.011

0.002

1.8E−08

KIAA0182

 

cg26723054

85650522

−0.038

0.007

7.2E−07

19

F2RL3

 

cg03636183g

17000585

−0.128

0.021

2.0E−08

DDA1

 

cg10664184

17420304

−0.028

0.004

9.2E−11

CD33

 

cg06861672

51727798

−0.036

0.007

3.3E−07

21

MIR155HG

 

cg03872783

26934885

−0.008

0.001

9.7E−07

  1. aChromosome
  2. bDistance to transcription start site of the mapped gene (basepair)
  3. cPhysical position (basepair, National Center for Biotechnology Information human reference genome assembly Build 37.3)
  4. dRegression coefficient from statistical model
  5. eStandard error of regression coefficient
  6. fStatistical significance from statistical model
  7. gProbe identified in previous epigenome-wide association studies (EWASs) of smoking
  8. hProbe mapped to genes identified in previous EWASs of smoking
  9. DMPs ordered by p values can be found in Additional file 10