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Table 3 Multivariate Cox regression analyses for baseline risk factors in DLBCL

From: Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma

Baseline risk factor

Hazard ratio

95 % hazard ratio confidence limits

P value

Lower

Upper

Age above 60 years

2.85

0.97

8.41

0.058

Male sex

4.10

1.41

11.92

0.010

Poor performance

5.36

1.56

18.41

0.008

Stage (III–IV)

0.44

0.13

1.42

0.169

Extranodal involvement

1.32

0.34

5.07

0.687

B symptoms

1.80

0.68

4.80

0.238

Not treated with rituximab

0.55

0.15

2.10

0.383

Elevated LDH

0.73

0.26

2.06

0.553

DAPK1 methylation

8.93

2.72

29.31

0.0007