Fig. 6

Methylation levels during treatment. Each plot shows the DAPK1 (green lines) and DBC1 (orange lines) methylation data acquired during treatment for an individual patient. Time of diagnosis is at week 0 and the treatment was initiated at the same time or 1–2 weeks after the first methylation measurement (start of solid lines). The last methylation measurement is indicated by the end of the solid lines. Time of death is indicated by a cross. Patients without a cross survived at least 5 years following their diagnosis. Patient 1 progressed to DLBCL from a follicular lymphoma. Response evaluations are displayed for each patient. CR complete response, PD progressive disease, N.D. no data