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Table 3 Pulse wave velocity (m/s) at age 9 years in relation to ANRIL DNA methylation

From: DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years

CpG

Hg19 coordinates

β value

p value

Adjusted p

1

chr9: 21993721

0.0089

0.803

0.770

2

chr9: 21993697

0.0173

0.622

0.592

3

chr9: 21993694

−0.053

0.357

0.723

4

chr9: 21993654

0.0016

0.967

0.621

5

chr9: 21993645

0.0663

0.037

0.026

6

chr9: 21993638

0.0207

0.583

0.345

7

chr9: 21993629

0.0154

0.736

0.659

8

chr9: 21993603

0.0258

0.531

0.322

9

chr9: 21993583

0.0828

0.176

0.087

  1. β values represent a 10 % change in methylation. DNA methylation levels were determined via pyrosequencing. Linear regressions were used to compare methylation and pulse wave velocity. Adjusted p values are adjusted for age, sex, total fat mass at 8 years and mother smoking during pregnancy
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Clinical Epigenetics

ISSN: 1868-7083

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