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Table 2 Heart rate (bpm) at age 9 years in relation to ANRIL promoter DNA methylation

From: DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years

CpG

Hg19 coordinates

β value

p value

Adjusted p

1

chr9: 21993721

−1.98

0.031

0.041

2

chr9: 21993697

−2.45

0.020

0.033

3

chr9: 21993694

−2.56

0.080

0.103

4

chr9: 21993654

−1.5

0.195

0.168

5

chr9: 21993645

−0.669

0.484

0.488

6

chr9: 21993638

−1.42

0.128

0.196

7

chr9: 21993629

0.096

0.938

0.936

8

chr9: 21993603

−1.18

0.288

0.402

9

chr9: 21993583

−0.626

0.642

0.463

  1. β values represent a 10 % change in methylation. DNA methylation levels were determined via pyrosequencing. Linear regressions were used to compare methylation and heart rate. Adjusted p values are adjusted for age, sex, total fat mass at 8 years and mother smoking during pregnancy
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Clinical Epigenetics

ISSN: 1868-7083

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