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Table 2 Familiality (%) of HIF3A DNA methylation and gene expression

From: DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance

 

Blood (h 2 %)

P

SAT (h 2 %)

P

Skeletal muscle (h 2 %)

P

HIF3A DNA methylation

 CpG 1 (cg22891070)

56 ± 25

0.008

55 ± 37

0.08

n.a.

 

 CpG 2

61 ± 27

0.01

44 ± 34

0.09

n.a.

 

 CpG 3 (cg16672562)

64 ± 24

0.003

34 ± 39

0.19

n.a.

 

 CpG 4

51 ± 26

0.02

41 ± 33

0.10

n.a.

 

HIF3A gene expression

n.a.

 

12 ± 20

0.26

43 ± 21

0.02

  1. Familiality estimates for the methylation and gene expression of HIF3A estimated using SOLAR software adjusted for age, sex, BMI, and HbA1c. Data are means ± SD
  2. n.a. not available
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Clinical Epigenetics

ISSN: 1868-7083

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