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Table 2 Familiality (%) of HIF3A DNA methylation and gene expression

From: DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance

  Blood (h 2 %) P SAT (h 2 %) P Skeletal muscle (h 2 %) P
HIF3A DNA methylation
 CpG 1 (cg22891070) 56 ± 25 0.008 55 ± 37 0.08 n.a.  
 CpG 2 61 ± 27 0.01 44 ± 34 0.09 n.a.  
 CpG 3 (cg16672562) 64 ± 24 0.003 34 ± 39 0.19 n.a.  
 CpG 4 51 ± 26 0.02 41 ± 33 0.10 n.a.  
HIF3A gene expression n.a.   12 ± 20 0.26 43 ± 21 0.02
  1. Familiality estimates for the methylation and gene expression of HIF3A estimated using SOLAR software adjusted for age, sex, BMI, and HbA1c. Data are means ± SD
  2. n.a. not available