Skip to main content

Advertisement

Table 1 Anthropometrical and metabolic characteristics of the family population

From: DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance

  Men (n = 51) Women (n = 86) P value
Age (years) 53.8 ± 12.0 53.9 ± 10.7 1.0
Weight (kg) 90.7 ± 16.8 76.3 ± 15.9 <0.0001
Height (cm) 177.2 ± 7.9 165.8 ± 6.4 <0.0001
BMI (kg/m2) 28.8 ± 3.8 27.90 ± 6.0 0.4
Glucose tolerance status
 NGT (normal glucose tolerance) 26 (51 %) 61 (71 %)  
 IFG (impaired fasting glucose) 3 (6 %) 4 (5 %)  
 IGT (impaired glucose tolerance) 10 (20 %) 7 (8 %)  
 T2D (type 2 diabetes mellitus) 12 (24 %) 14 (16 %)  
Fasting glucose (mmol/l) 6.9 ± 3.0 6.0 ± 2.1 0.02
Fasting insulin (pmol/l) 54.3 ± 35.5 46.2 ± 41.0 0.05
HbA1c (%) 5.8 ± 1.3 5.7 ± 1.0 0.6
Whole-body insulin sensitivity 6.27 ± 4.06 8.73 ± 5.29 0.007
  1. All values are means ± SD. Fasting glucose, fasting insulin, and HbA1c values were logarithmically transformed to obtain normal distribution prior to analysis. P values were calculated in R 3.1.0 using a mixed linear model with family number as a random factor and sex, age, and BMI as a fixed factor. Glucose tolerance status: numbers (and percentage) of NGT, IFG, IGT, and T2D individuals