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Fig. 2 | Clinical Epigenetics

Fig. 2

From: p38-MAPK/MSK1-mediated overexpression of histone H3 serine 10 phosphorylation defines distance-dependent prognostic value of negative resection margin in gastric cancer

Fig. 2

Effect of H3S10ph levels of tumor, PRM, and DRM on GC patients’ survival. Kaplan-Meier survival analysis was done according to H3S10ph staining H-score: low (0–100), intermediate (100–200), and high (200–300). High level of H3S10P of tumor and PRM and DRM is associated with both poor overall survival (OS) and disease-free survival (DFS). a OS and DFS based on H3S10P levels of tumor tissues, b OS and DFS based on H3S10P levels of PRM tissues, c OS and DFS based on H3S10P levels of DRM tissues. GC gastric cancer, PRM proximal resection margin, DRM distal resection margin, Int. intermediate. Comparison was done by log-rank test. p < 0.05 was considered as significant

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