TY - JOUR AU - Pleyer, L. AU - Greil, R. PY - 2015 DA - 2015// TI - Digging deep into “dirty” drugs—modulation of the methylation machinery JO - Drug Metab Rev VL - 47 UR - https://doi.org/10.3109/03602532.2014.995379 DO - 10.3109/03602532.2014.995379 ID - Pleyer2015 ER - TY - JOUR AU - Baylin, S. B. PY - 2005 DA - 2005// TI - DNA methylation and gene silencing in cancer JO - Nat Clin Pract Oncol VL - 2 UR - https://doi.org/10.1038/ncponc0354 DO - 10.1038/ncponc0354 ID - Baylin2005 ER - TY - JOUR AU - Herman, J. G. AU - Merlo, A. AU - Mao, L. AU - Lapidus, R. G. AU - Issa, J. P. AU - Davidson, N. E. PY - 1995 DA - 1995// TI - Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers JO - Cancer Res VL - 55 ID - Herman1995 ER - TY - JOUR AU - Das, P. M. AU - Singal, R. PY - 2004 DA - 2004// TI - DNA methylation and cancer JO - J Clin Oncol VL - 22 UR - https://doi.org/10.1200/JCO.2004.07.151 DO - 10.1200/JCO.2004.07.151 ID - Das2004 ER - TY - JOUR AU - Plass, C. AU - Pfister, S. M. AU - Lindroth, A. M. AU - Bogatyrova, O. AU - Claus, R. AU - Lichter, P. PY - 2013 DA - 2013// TI - Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer JO - Nat Rev Genet VL - 14 UR - https://doi.org/10.1038/nrg3554 DO - 10.1038/nrg3554 ID - Plass2013 ER - TY - JOUR AU - Shen, L. AU - Song, C. X. AU - He, C. AU - Zhang, Y. PY - 2014 DA - 2014// TI - Mechanism and function of oxidative reversal of DNA and RNA methylation JO - Annu Rev Biochem VL - 83 UR - https://doi.org/10.1146/annurev-biochem-060713-035513 DO - 10.1146/annurev-biochem-060713-035513 ID - Shen2014 ER - TY - JOUR AU - Sedgwick, B. PY - 2004 DA - 2004// TI - Repairing DNA-methylation damage JO - Nat Rev Mol Cell Biol VL - 5 UR - https://doi.org/10.1038/nrm1312 DO - 10.1038/nrm1312 ID - Sedgwick2004 ER - TY - JOUR AU - Niehrs, C. AU - Schafer, A. PY - 2012 DA - 2012// TI - Active DNA demethylation by Gadd45 and DNA repair JO - Trends Cell Biol VL - 22 UR - https://doi.org/10.1016/j.tcb.2012.01.002 DO - 10.1016/j.tcb.2012.01.002 ID - Niehrs2012 ER - TY - JOUR AU - Shen, H. AU - Laird, P. W. PY - 2013 DA - 2013// TI - Interplay between the cancer genome and epigenome JO - Cell VL - 153 UR - https://doi.org/10.1016/j.cell.2013.03.008 DO - 10.1016/j.cell.2013.03.008 ID - Shen2013 ER - TY - JOUR AU - Baubec, T. AU - Ivanek, R. AU - Lienert, F. AU - Schubeler, D. PY - 2013 DA - 2013// TI - Methylation-dependent and -independent genomic targeting principles of the MBD protein family JO - Cell VL - 153 UR - https://doi.org/10.1016/j.cell.2013.03.011 DO - 10.1016/j.cell.2013.03.011 ID - Baubec2013 ER - TY - JOUR AU - Cartron, P. F. AU - Nadaradjane, A. AU - Lepape, F. AU - Lalier, L. AU - Gardie, B. AU - Vallette, F. M. PY - 2013 DA - 2013// TI - Identification of TET1 partners that control its DNA-demethylating function JO - Genes Cancer VL - 4 UR - https://doi.org/10.1177/1947601913489020 DO - 10.1177/1947601913489020 ID - Cartron2013 ER - TY - JOUR AU - Prensner, J. R. AU - Chinnaiyan, A. M. PY - 2011 DA - 2011// TI - Metabolism unhinged: IDH mutations in cancer JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm0311-291 DO - 10.1038/nm0311-291 ID - Prensner2011 ER - TY - JOUR AU - Suetake, I. AU - Shinozaki, F. AU - Miyagawa, J. AU - Takeshima, H. AU - Tajima, S. PY - 2004 DA - 2004// TI - DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M400181200 DO - 10.1074/jbc.M400181200 ID - Suetake2004 ER - TY - JOUR AU - Ulrich, C. M. AU - Robien, K. AU - McLeod, H. L. PY - 2003 DA - 2003// TI - Cancer pharmacogenetics: polymorphisms, pathways and beyond JO - Nat Rev Cancer VL - 3 UR - https://doi.org/10.1038/nrc1233 DO - 10.1038/nrc1233 ID - Ulrich2003 ER - TY - JOUR AU - Nazki, F. H. AU - Sameer, A. S. AU - Ganaie, B. A. PY - 2014 DA - 2014// TI - Folate: metabolism, genes, polymorphisms and the associated diseases JO - Gene VL - 533 UR - https://doi.org/10.1016/j.gene.2013.09.063 DO - 10.1016/j.gene.2013.09.063 ID - Nazki2014 ER - TY - JOUR AU - Kim, Y. I. PY - 2005 DA - 2005// TI - Nutritional epigenetics: impact of folate deficiency on DNA methylation and colon cancer susceptibility JO - J Nutr VL - 135 ID - Kim2005 ER - TY - JOUR AU - Stover, P. J. PY - 2011 DA - 2011// TI - Polymorphisms in 1-carbon metabolism, epigenetics and folate-related pathologies JO - J Nutrigenet Nutrigenomics VL - 4 UR - https://doi.org/10.1159/000334586 DO - 10.1159/000334586 ID - Stover2011 ER - TY - JOUR AU - Fox, J. T. AU - Stover, P. J. PY - 2008 DA - 2008// TI - Folate-mediated one-carbon metabolism JO - Vitam Horm VL - 79 UR - https://doi.org/10.1016/S0083-6729(08)00401-9 DO - 10.1016/S0083-6729(08)00401-9 ID - Fox2008 ER - TY - JOUR AU - Kelemen, L. E. PY - 2006 DA - 2006// TI - The role of folate receptor alpha in cancer development, progression and treatment: cause, consequence or innocent bystander? JO - Int J Cancer VL - 119 UR - https://doi.org/10.1002/ijc.21712 DO - 10.1002/ijc.21712 ID - Kelemen2006 ER - TY - JOUR AU - Andreassi, M. G. AU - Botto, N. AU - Cocci, F. AU - Battaglia, D. AU - Antonioli, E. AU - Masetti, S. PY - 2003 DA - 2003// TI - Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease JO - Hum Genet VL - 112 ID - Andreassi2003 ER - TY - JOUR AU - Figueiredo, J. C. AU - Levine, A. J. AU - Crott, J. W. AU - Baurley, J. AU - Haile, R. W. PY - 2013 DA - 2013// TI - Folate-genetics and colorectal neoplasia: what we know and need to know next JO - Mol Nutr Food Res VL - 57 UR - https://doi.org/10.1002/mnfr.201200278 DO - 10.1002/mnfr.201200278 ID - Figueiredo2013 ER - TY - JOUR AU - Lightfoot, T. J. AU - Johnston, W. T. AU - Painter, D. AU - Simpson, J. AU - Roman, E. AU - Skibola, C. F. PY - 2010 DA - 2010// TI - Genetic variation in the folate metabolic pathway and risk of childhood leukemia JO - Blood VL - 115 UR - https://doi.org/10.1182/blood-2009-10-249722 DO - 10.1182/blood-2009-10-249722 ID - Lightfoot2010 ER - TY - JOUR AU - Zhang, H. AU - Liu, C. AU - Han, Y. C. AU - Ma, Z. AU - Zhang, H. AU - Ma, Y. PY - 2015 DA - 2015// TI - Genetic variations in the one-carbon metabolism pathway genes and susceptibility to hepatocellular carcinoma risk: a case-control study JO - Tumour Biol VL - 36 UR - https://doi.org/10.1007/s13277-014-2725-z DO - 10.1007/s13277-014-2725-z ID - Zhang2015 ER - TY - JOUR AU - Vazquez, A. AU - Tedeschi, P. M. AU - Bertino, J. R. PY - 2013 DA - 2013// TI - Overexpression of the mitochondrial folate and glycine-serine pathway: a new determinant of methotrexate selectivity in tumors JO - Cancer Res VL - 73 UR - https://doi.org/10.1158/0008-5472.CAN-12-3709 DO - 10.1158/0008-5472.CAN-12-3709 ID - Vazquez2013 ER - TY - JOUR AU - Martinelli, M. AU - Scapoli, L. AU - Mattei, G. AU - Ugolini, G. AU - Montroni, I. AU - Zattoni, D. PY - 2013 DA - 2013// TI - A candidate gene study of one-carbon metabolism pathway genes and colorectal cancer risk JO - Br J Nutr VL - 109 UR - https://doi.org/10.1017/S0007114512002796 DO - 10.1017/S0007114512002796 ID - Martinelli2013 ER - TY - JOUR AU - Yu, W. AU - Jin, C. AU - Lou, X. AU - Han, X. AU - Li, L. AU - He, Y. PY - 2011 DA - 2011// TI - Global analysis of DNA methylation by methyl-capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0029450 DO - 10.1371/journal.pone.0029450 ID - Yu2011 ER - TY - JOUR AU - Hagner, N. AU - Joerger, M. PY - 2010 DA - 2010// TI - Cancer chemotherapy: targeting folic acid synthesis JO - Cancer Manag Res VL - 2 ID - Hagner2010 ER - TY - JOUR AU - Jakopovic, M. AU - Thomas, A. AU - Balasubramaniam, S. AU - Schrump, D. AU - Giaccone, G. AU - Bates, S. E. PY - 2013 DA - 2013// TI - Targeting the epigenome in lung cancer: expanding approaches to epigenetic therapy JO - Front Oncol VL - 3 UR - https://doi.org/10.3389/fonc.2013.00261 DO - 10.3389/fonc.2013.00261 ID - Jakopovic2013 ER - TY - JOUR AU - Matherly, L. H. AU - Wilson, M. R. AU - Hou, Z. PY - 2014 DA - 2014// TI - The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer JO - Drug Metab Dispos VL - 42 UR - https://doi.org/10.1124/dmd.113.055723 DO - 10.1124/dmd.113.055723 ID - Matherly2014 ER - TY - JOUR AU - Fahy, J. AU - Jeltsch, A. AU - Arimondo, P. B. PY - 2012 DA - 2012// TI - DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies JO - Expert Opin Ther Pat VL - 22 UR - https://doi.org/10.1517/13543776.2012.729579 DO - 10.1517/13543776.2012.729579 ID - Fahy2012 ER - TY - JOUR AU - Holbeck, S. L. AU - Collins, J. M. AU - Doroshow, J. H. PY - 2010 DA - 2010// TI - Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines JO - Mol Cancer Ther VL - 9 UR - https://doi.org/10.1158/1535-7163.MCT-10-0106 DO - 10.1158/1535-7163.MCT-10-0106 ID - Holbeck2010 ER - TY - JOUR AU - Schneider-Stock, R. AU - Diab-Assef, M. AU - Rohrbeck, A. AU - Foltzer-Jourdainne, C. AU - Boltze, C. AU - Hartig, R. PY - 2005 DA - 2005// TI - 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms JO - J Pharmacol Exp Ther VL - 312 UR - https://doi.org/10.1124/jpet.104.074195 DO - 10.1124/jpet.104.074195 ID - Schneider-Stock2005 ER - TY - STD TI - Patel AG, Kaufmann SH. How does doxorubicin work? Elife. 2012;1. e00387. ID - ref33 ER - TY - JOUR AU - Yokochi, T. AU - Robertson, K. D. PY - 2004 DA - 2004// TI - Doxorubicin inhibits DNMT1, resulting in conditional apoptosis JO - Mol Pharmacol VL - 66 UR - https://doi.org/10.1124/mol.104.002634 DO - 10.1124/mol.104.002634 ID - Yokochi2004 ER - TY - JOUR AU - Alakhova, D. Y. AU - Zhao, Y. AU - Li, S. AU - Kabanov, A. V. PY - 2013 DA - 2013// TI - Effect of doxorubicin/pluronic SP1049C on tumorigenicity, aggressiveness, DNA methylation and stem cell markers in murine leukemia JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0072238 DO - 10.1371/journal.pone.0072238 ID - Alakhova2013 ER - TY - JOUR AU - Li, C. T. AU - Hsiao, Y. M. AU - Wu, T. C. AU - Lin, Y. W. AU - Yeh, K. T. AU - Ko, J. L. PY - 2011 DA - 2011// TI - Vorinostat, SAHA, represses telomerase activity via epigenetic regulation of telomerase reverse transcriptase in non-small cell lung cancer cells JO - J Cell Biochem VL - 112 UR - https://doi.org/10.1002/jcb.23229 DO - 10.1002/jcb.23229 ID - Li2011 ER - TY - STD TI - Lee J, R SH. Cancer epigenetics: mechanisms and crosstalk of a HDAC inhibitor, vorinostat. Chemotherapy (Los Angel). 2013;2:14934. doi: 10.4172/2167-7700.1000111. ID - ref37 ER - TY - JOUR AU - Zhou, X. AU - Yang, X. Y. AU - Popescu, N. C. PY - 2012 DA - 2012// TI - Preclinical evaluation of combined antineoplastic effect of DLC1 tumor suppressor protein and suberoylanilide hydroxamic acid on prostate cancer cells JO - Biochem Biophys Res Commun VL - 420 UR - https://doi.org/10.1016/j.bbrc.2012.02.158 DO - 10.1016/j.bbrc.2012.02.158 ID - Zhou2012 ER - TY - JOUR AU - Fahrer, J. AU - Kaina, B. PY - 2013 DA - 2013// TI - O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer JO - Carcinogenesis VL - 34 UR - https://doi.org/10.1093/carcin/bgt275 DO - 10.1093/carcin/bgt275 ID - Fahrer2013 ER - TY - JOUR AU - Brown, R. AU - Curry, E. AU - Magnani, L. AU - Wilhelm-Benartzi, C. S. AU - Borley, J. PY - 2014 DA - 2014// TI - Poised epigenetic states and acquired drug resistance in cancer JO - Nat Rev Cancer VL - 14 UR - https://doi.org/10.1038/nrc3819 DO - 10.1038/nrc3819 ID - Brown2014 ER - TY - JOUR AU - Heyn, H. AU - Esteller, M. PY - 2012 DA - 2012// TI - DNA methylation profiling in the clinic: applications and challenges JO - Nat Rev Genet VL - 13 UR - https://doi.org/10.1038/nrg3270 DO - 10.1038/nrg3270 ID - Heyn2012 ER - TY - JOUR AU - Siddik, Z. H. PY - 2003 DA - 2003// TI - Cisplatin: mode of cytotoxic action and molecular basis of resistance JO - Oncogene VL - 22 UR - https://doi.org/10.1038/sj.onc.1206933 DO - 10.1038/sj.onc.1206933 ID - Siddik2003 ER - TY - JOUR AU - Shen, D. W. AU - Pouliot, L. M. AU - Hall, M. D. AU - Gottesman, M. M. PY - 2012 DA - 2012// TI - Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes JO - Pharmacol Rev VL - 64 UR - https://doi.org/10.1124/pr.111.005637 DO - 10.1124/pr.111.005637 ID - Shen2012 ER - TY - JOUR AU - Zeller, C. AU - Dai, W. AU - Steele, N. L. AU - Siddiq, A. AU - Walley, A. J. AU - Wilhelm-Benartzi, C. S. PY - 2012 DA - 2012// TI - Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling JO - Oncogene VL - 31 UR - https://doi.org/10.1038/onc.2011.611 DO - 10.1038/onc.2011.611 ID - Zeller2012 ER - TY - JOUR AU - Zhang, Y. W. AU - Zheng, Y. AU - Wang, J. Z. AU - Lu, X. X. AU - Wang, Z. AU - Chen, L. B. PY - 2014 DA - 2014// TI - Integrated analysis of DNA methylation and mRNA expression profiling reveals candidate genes associated with cisplatin resistance in non-small cell lung cancer JO - Epigenetics VL - 9 UR - https://doi.org/10.4161/epi.28601 DO - 10.4161/epi.28601 ID - Zhang2014 ER - TY - JOUR AU - Rosell, R. AU - Taron, M. AU - Massuti, B. AU - Mederos, N. AU - Magri, I. AU - Santarpia, M. PY - 2011 DA - 2011// TI - Predicting response to chemotherapy with early-stage lung cancer JO - Cancer J VL - 17 UR - https://doi.org/10.1097/PPO.0b013e3182091fa3 DO - 10.1097/PPO.0b013e3182091fa3 ID - Rosell2011 ER - TY - JOUR AU - Weger, V. A. AU - Beijnen, J. H. AU - Schellens, J. H. PY - 2014 DA - 2014// TI - Cellular and clinical pharmacology of the taxanes docetaxel and paclitaxel—a review JO - Anticancer Drugs VL - 25 UR - https://doi.org/10.1097/CAD.0000000000000093 DO - 10.1097/CAD.0000000000000093 ID - Weger2014 ER - TY - JOUR AU - Das, G. C. AU - Holiday, D. AU - Gallardo, R. AU - Haas, C. PY - 2001 DA - 2001// TI - Taxol-induced cell cycle arrest and apoptosis: dose-response relationship in lung cancer cells of different wild-type p53 status and under isogenic condition JO - Cancer Lett VL - 165 UR - https://doi.org/10.1016/S0304-3835(01)00404-9 DO - 10.1016/S0304-3835(01)00404-9 ID - Das2001 ER - TY - JOUR AU - Flanagan, J. M. AU - Wilhelm-Benartzi, C. S. AU - Metcalf, M. AU - Kaye, S. B. AU - Brown, R. PY - 2013 DA - 2013// TI - Association of somatic DNA methylation variability with progression-free survival and toxicity in ovarian cancer patients JO - Ann Oncol VL - 24 UR - https://doi.org/10.1093/annonc/mdt370 DO - 10.1093/annonc/mdt370 ID - Flanagan2013 ER - TY - JOUR AU - Yun, T. AU - Liu, Y. AU - Gao, D. AU - Linghu, E. AU - Brock, M. V. AU - Yin, D. PY - 2015 DA - 2015// TI - Methylation of CHFR sensitizes esophageal squamous cell cancer to docetaxel and paclitaxel JO - Genes Cancer VL - 6 ID - Yun2015 ER - TY - JOUR AU - Monks, A. AU - Scudiero, D. AU - Skehan, P. AU - Shoemaker, R. AU - Paull, K. AU - Vistica, D. PY - 1991 DA - 1991// TI - Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines JO - J Natl Cancer Inst VL - 83 UR - https://doi.org/10.1093/jnci/83.11.757 DO - 10.1093/jnci/83.11.757 ID - Monks1991 ER - TY - JOUR AU - Murphy, S. K. PY - 2012 DA - 2012// TI - Targeting the epigenome in ovarian cancer JO - Future Oncol VL - 8 UR - https://doi.org/10.2217/fon.11.152 DO - 10.2217/fon.11.152 ID - Murphy2012 ER - TY - JOUR AU - Nguyen, A. N. AU - Hollenbach, P. W. AU - Richard, N. AU - Luna-Moran, A. AU - Brady, H. AU - Heise, C. PY - 2010 DA - 2010// TI - Azacitidine and decitabine have different mechanisms of action in non-small cell lung cancer cell lines JO - Lung Cancer VL - 1 ID - Nguyen2010 ER - TY - JOUR AU - Barreto, G. AU - Schafer, A. AU - Marhold, J. AU - Stach, D. AU - Swaminathan, S. K. AU - Handa, V. PY - 2007 DA - 2007// TI - Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation JO - Nature VL - 445 UR - https://doi.org/10.1038/nature05515 DO - 10.1038/nature05515 ID - Barreto2007 ER - TY - JOUR AU - Xu, J. AU - Zhu, W. AU - Xu, W. AU - Cui, X. AU - Chen, L. AU - Ji, S. PY - 2013 DA - 2013// TI - Silencing of MBD1 reverses pancreatic cancer therapy resistance through inhibition of DNA damage repair JO - Int J Oncol VL - 42 ID - Xu2013 ER - TY - JOUR AU - Prokhortchouk, E. AU - Hendrich, B. PY - 2002 DA - 2002// TI - Methyl-CpG binding proteins and cancer: are MeCpGs more important than MBDs? JO - Oncogene VL - 21 UR - https://doi.org/10.1038/sj.onc.1205631 DO - 10.1038/sj.onc.1205631 ID - Prokhortchouk2002 ER - TY - JOUR AU - Cheishvili, D. AU - Chik, F. AU - Li, C. C. AU - Bhattacharya, B. AU - Suderman, M. AU - Arakelian, A. PY - 2014 DA - 2014// TI - Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2′-deoxycytidine-triggered invasiveness JO - Carcinogenesis VL - 35 UR - https://doi.org/10.1093/carcin/bgu181 DO - 10.1093/carcin/bgu181 ID - Cheishvili2014 ER - TY - JOUR AU - Zhao, R. AU - Goldman, I. D. PY - 2013 DA - 2013// TI - Folate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors JO - Mol Aspects Med VL - 34 UR - https://doi.org/10.1016/j.mam.2012.07.006 DO - 10.1016/j.mam.2012.07.006 ID - Zhao2013 ER - TY - JOUR AU - Hou, Z. AU - Matherly, L. H. PY - 2014 DA - 2014// TI - Biology of the major facilitative folate transporters SLC19A1 and SLC46A1 JO - Curr Top Membr VL - 73 UR - https://doi.org/10.1016/B978-0-12-800223-0.00004-9 DO - 10.1016/B978-0-12-800223-0.00004-9 ID - Hou2014 ER - TY - JOUR AU - Murray, B. AU - Antonyuk, S. V. AU - Marina, A. AU - Liempd, S. M. AU - Lu, S. C. AU - Mato, J. M. PY - 2014 DA - 2014// TI - Structure and function study of the complex that synthesizes S-adenosylmethionine JO - IUCrJ VL - 1 UR - https://doi.org/10.1107/S2052252514012585 DO - 10.1107/S2052252514012585 ID - Murray2014 ER - TY - JOUR AU - Wang, Y. C. AU - Chiang, E. P. PY - 2012 DA - 2012// TI - Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo JO - Mol Med VL - 18 ID - Wang2012 ER - TY - JOUR AU - Iacobazzi, V. AU - Castegna, A. AU - Infantino, V. AU - Andria, G. PY - 2013 DA - 2013// TI - Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool JO - Mol Genet Metab VL - 110 UR - https://doi.org/10.1016/j.ymgme.2013.07.012 DO - 10.1016/j.ymgme.2013.07.012 ID - Iacobazzi2013 ER - TY - JOUR AU - Tehlivets, O. AU - Malanovic, N. AU - Visram, M. AU - Pavkov-Keller, T. AU - Keller, W. PY - 1832 DA - 1832// TI - S-adenosyl-L-homocysteine hydrolase and methylation disorders: yeast as a model system JO - Biochim Biophys Acta VL - 2013 ID - Tehlivets1832 ER - TY - JOUR AU - Blom, H. J. AU - Smulders, Y. PY - 2011 DA - 2011// TI - Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects JO - J Inherit Metab Dis VL - 34 UR - https://doi.org/10.1007/s10545-010-9177-4 DO - 10.1007/s10545-010-9177-4 ID - Blom2011 ER - TY - JOUR AU - Bhatla, T. AU - Wang, J. AU - Morrison, D. J. AU - Raetz, E. A. AU - Burke, M. J. AU - Brown, P. PY - 2012 DA - 2012// TI - Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia JO - Blood VL - 119 UR - https://doi.org/10.1182/blood-2012-01-401687 DO - 10.1182/blood-2012-01-401687 ID - Bhatla2012 ER - TY - JOUR AU - LaBonte, M. J. AU - Wilson, P. M. AU - Fazzone, W. AU - Groshen, S. AU - Lenz, H. J. AU - Ladner, R. D. PY - 2009 DA - 2009// TI - DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines JO - BMC Med Genomics VL - 2 UR - https://doi.org/10.1186/1755-8794-2-67 DO - 10.1186/1755-8794-2-67 ID - LaBonte2009 ER - TY - JOUR AU - Gennaro, E. AU - Bruzzese, F. AU - Pepe, S. AU - Leone, A. AU - Delrio, P. AU - Subbarayan, P. R. PY - 2009 DA - 2009// TI - Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed JO - Cancer Biol Ther VL - 8 UR - https://doi.org/10.4161/cbt.8.9.8118 DO - 10.4161/cbt.8.9.8118 ID - Gennaro2009 ER - TY - JOUR AU - Lee, S. J. AU - Hwang, S. O. AU - Noh, E. J. AU - Kim, D. U. AU - Nam, M. AU - Kim, J. H. PY - 2014 DA - 2014// TI - Transactivation of bad by vorinostat-induced acetylated p53 enhances doxorubicin-induced cytotoxicity in cervical cancer cells JO - Exp Mol Med VL - 46 UR - https://doi.org/10.1038/emm.2013.149 DO - 10.1038/emm.2013.149 ID - Lee2014 ER - TY - JOUR AU - Ulanovskaya, O. A. AU - Zuhl, A. M. AU - Cravatt, B. F. PY - 2013 DA - 2013// TI - NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink JO - Nat Chem Biol VL - 9 UR - https://doi.org/10.1038/nchembio.1204 DO - 10.1038/nchembio.1204 ID - Ulanovskaya2013 ER - TY - JOUR AU - Shlomi, T. AU - Rabinowitz, J. D. PY - 2013 DA - 2013// TI - Metabolism: cancer mistunes methylation JO - Nat Chem Biol VL - 9 UR - https://doi.org/10.1038/nchembio.1234 DO - 10.1038/nchembio.1234 ID - Shlomi2013 ER - TY - JOUR AU - Ghoshal, K. AU - Datta, J. AU - Majumder, S. AU - Bai, S. AU - Kutay, H. AU - Motiwala, T. PY - 2005 DA - 2005// TI - 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal JO - Mol Cell Biol VL - 25 UR - https://doi.org/10.1128/MCB.25.11.4727-4741.2005 DO - 10.1128/MCB.25.11.4727-4741.2005 ID - Ghoshal2005 ER - TY - JOUR AU - Liberzon, A. AU - Subramanian, A. AU - Pinchback, R. AU - Thorvaldsdottir, H. AU - Tamayo, P. AU - Mesirov, J. P. PY - 2011 DA - 2011// TI - Molecular signatures database (MSigDB) 3.0 JO - Bioinformatics VL - 27 UR - https://doi.org/10.1093/bioinformatics/btr260 DO - 10.1093/bioinformatics/btr260 ID - Liberzon2011 ER - TY - JOUR AU - Wang, W. AU - Huper, G. AU - Guo, Y. AU - Murphy, S. K. AU - Olson, J. A. AU - Marks, J. R. PY - 2005 DA - 2005// TI - Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer JO - Oncogene VL - 24 UR - https://doi.org/10.1038/sj.onc.1208464 DO - 10.1038/sj.onc.1208464 ID - Wang2005 ER - TY - JOUR AU - Franchini, D. M. AU - Petersen-Mahrt, S. K. PY - 2014 DA - 2014// TI - AID and APOBEC deaminases: balancing DNA damage in epigenetics and immunity JO - Epigenomics VL - 6 UR - https://doi.org/10.2217/epi.14.35 DO - 10.2217/epi.14.35 ID - Franchini2014 ER - TY - JOUR AU - Bronner, C. PY - 2011 DA - 2011// TI - Control of DNMT1 abundance in epigenetic inheritance by acetylation, ubiquitylation, and the histone code JO - Sci Signal VL - 4 UR - https://doi.org/10.1126/scisignal.2001764 DO - 10.1126/scisignal.2001764 ID - Bronner2011 ER - TY - STD TI - Varol N, Konac E, Bilen CY. Does Wnt/beta-catenin pathway contribute to the stability of DNMT1 expression in urological cancer cell lines? Exp Biol Med (Maywood). 2014. ID - ref76 ER - TY - JOUR AU - Ji, Y. AU - Nordgren, K. K. AU - Chai, Y. AU - Hebbring, S. J. AU - Jenkins, G. D. AU - Abo, R. P. PY - 2012 DA - 2012// TI - Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation JO - Drug Metab Dispos VL - 40 UR - https://doi.org/10.1124/dmd.112.046953 DO - 10.1124/dmd.112.046953 ID - Ji2012 ER - TY - JOUR AU - Lee, M. S. AU - Bonner, J. R. AU - Bernard, D. J. AU - Sanchez, E. L. AU - Sause, E. T. AU - Prentice, R. R. PY - 2012 DA - 2012// TI - Disruption of the folate pathway in zebrafish causes developmental defects JO - BMC Dev Biol VL - 12 UR - https://doi.org/10.1186/1471-213X-12-12 DO - 10.1186/1471-213X-12-12 ID - Lee2012 ER - TY - JOUR AU - Hazra, A. AU - Wu, K. AU - Kraft, P. AU - Fuchs, C. S. AU - Giovannucci, E. L. AU - Hunter, D. J. PY - 2007 DA - 2007// TI - Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the Nurses’ Health Study JO - Carcinogenesis VL - 28 UR - https://doi.org/10.1093/carcin/bgm062 DO - 10.1093/carcin/bgm062 ID - Hazra2007 ER - TY - JOUR AU - Lau, D. T. AU - Hesson, L. B. AU - Norris, M. D. AU - Marshall, G. M. AU - Haber, M. AU - Ashton, L. J. PY - 2012 DA - 2012// TI - Prognostic significance of promoter DNA methylation in patients with childhood neuroblastoma JO - Clin Cancer Res VL - 18 UR - https://doi.org/10.1158/1078-0432.CCR-12-0294 DO - 10.1158/1078-0432.CCR-12-0294 ID - Lau2012 ER - TY - JOUR AU - Stewart, D. J. AU - Nunez, M. I. AU - Jelinek, J. AU - Hong, D. AU - Gupta, S. AU - Issa, J. P. PY - 2014 DA - 2014// TI - Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors JO - Clin Epigenetics VL - 6 UR - https://doi.org/10.1186/1868-7083-6-2 DO - 10.1186/1868-7083-6-2 ID - Stewart2014 ER - TY - JOUR AU - Cong, X. AU - Lu, C. AU - Huang, X. AU - Yang, D. AU - Cui, X. AU - Cai, J. PY - 2014 DA - 2014// TI - Increased expression of glycinamide ribonucleotide transformylase is associated with a poor prognosis in hepatocellular carcinoma, and it promotes liver cancer cell proliferation JO - Hum Pathol VL - 45 UR - https://doi.org/10.1016/j.humpath.2013.11.021 DO - 10.1016/j.humpath.2013.11.021 ID - Cong2014 ER - TY - JOUR AU - Liu, X. AU - Ding, Z. AU - Liu, Y. AU - Zhang, J. AU - Liu, F. AU - Wang, X. PY - 2014 DA - 2014// TI - Glycinamide ribonucleotide formyl transferase is frequently overexpressed in glioma and critically regulates the proliferation of glioma cells JO - Pathol Res Pract VL - 210 UR - https://doi.org/10.1016/j.prp.2013.10.009 DO - 10.1016/j.prp.2013.10.009 ID - Liu2014 ER - TY - JOUR AU - Shin, M. AU - Bryant, J. D. AU - Momb, J. AU - Appling, D. R. PY - 2014 DA - 2014// TI - Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues JO - J Biol Chem VL - 289 UR - https://doi.org/10.1074/jbc.M114.555573 DO - 10.1074/jbc.M114.555573 ID - Shin2014 ER - TY - JOUR AU - Zhu, W. G. AU - Hileman, T. AU - Ke, Y. AU - Wang, P. AU - Lu, S. AU - Duan, W. PY - 2004 DA - 2004// TI - 5-aza-2′-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M311703200 DO - 10.1074/jbc.M311703200 ID - Zhu2004 ER - TY - JOUR AU - Christman, J. K. PY - 2002 DA - 2002// TI - 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy JO - Oncogene VL - 21 UR - https://doi.org/10.1038/sj.onc.1205699 DO - 10.1038/sj.onc.1205699 ID - Christman2002 ER - TY - JOUR AU - Arai, M. AU - Yokosuka, O. AU - Hirasawa, Y. AU - Fukai, K. AU - Chiba, T. AU - Imazeki, F. PY - 2006 DA - 2006// TI - Sequential gene expression changes in cancer cell lines after treatment with the demethylation agent 5-aza-2′-deoxycytidine JO - Cancer VL - 106 UR - https://doi.org/10.1002/cncr.21905 DO - 10.1002/cncr.21905 ID - Arai2006 ER - TY - JOUR AU - Mossman, D. AU - Kim, K. T. AU - Scott, R. J. PY - 2010 DA - 2010// TI - Demethylation by 5-aza-2′-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists JO - BMC Cancer VL - 10 UR - https://doi.org/10.1186/1471-2407-10-366 DO - 10.1186/1471-2407-10-366 ID - Mossman2010 ER - TY - JOUR AU - Hossain, M. Z. AU - Healey, M. A. AU - Lee, C. AU - Poh, W. AU - Yerram, S. R. AU - Patel, K. PY - 2013 DA - 2013// TI - DNA-intercalators causing rapid re-expression of methylated and silenced genes in cancer cells JO - Oncotarget VL - 4 UR - https://doi.org/10.18632/oncotarget.863 DO - 10.18632/oncotarget.863 ID - Hossain2013 ER - TY - JOUR AU - Song, D. AU - Ni, J. AU - Xie, H. AU - Ding, M. AU - Wang, J. PY - 2014 DA - 2014// TI - DNA demethylation in the PTEN gene promoter induced by 5-azacytidine activates PTEN expression in the MG-63 human osteosarcoma cell line JO - Exp Ther Med VL - 7 ID - Song2014 ER - TY - JOUR AU - Qu, Y. AU - Dang, S. AU - Hou, P. PY - 2013 DA - 2013// TI - Gene methylation in gastric cancer JO - Clin Chim Acta VL - 424 UR - https://doi.org/10.1016/j.cca.2013.05.002 DO - 10.1016/j.cca.2013.05.002 ID - Qu2013 ER - TY - JOUR AU - Li, L. C. AU - Okino, S. T. AU - Dahiya, R. PY - 1704 DA - 1704// TI - DNA methylation in prostate cancer JO - Biochim Biophys Acta VL - 2004 ID - Li1704 ER - TY - JOUR AU - Liu, L. AU - Vo, A. AU - McKeehan, W. L. PY - 2005 DA - 2005// TI - Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5 JO - Cancer Res VL - 65 UR - https://doi.org/10.1158/0008-5472.CAN-04-3896 DO - 10.1158/0008-5472.CAN-04-3896 ID - Liu2005 ER - TY - CHAP AU - Mohan, V. AU - Madhusudan, S. ED - Chen, C. PY - 2013 DA - 2013// TI - DNA base excision repair: evolving biomarkers for personalized therapies in cancer BT - Evolving drug targets in DNA base excision repair for cancer therapy ID - Mohan2013 ER - TY - JOUR AU - Teng, Y. W. AU - Mehedint, M. G. AU - Garrow, T. A. AU - Zeisel, S. H. PY - 2011 DA - 2011// TI - Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas JO - J Biol Chem VL - 286 UR - https://doi.org/10.1074/jbc.M111.265348 DO - 10.1074/jbc.M111.265348 ID - Teng2011 ER - TY - JOUR AU - Li, Q. AU - Mao, L. AU - Wang, R. AU - Zhu, L. AU - Xue, L. PY - 2014 DA - 2014// TI - Overexpression of S-adenosylhomocysteine hydrolase (SAHH) in esophageal squamous cell carcinoma (ESCC) cell lines: effects on apoptosis, migration and adhesion of cells JO - Mol Biol Rep VL - 41 UR - https://doi.org/10.1007/s11033-014-3095-8 DO - 10.1007/s11033-014-3095-8 ID - Li2014 ER - TY - JOUR AU - Otani, T. AU - Iwasaki, M. AU - Hanaoka, T. AU - Kobayashi, M. AU - Ishihara, J. AU - Natsukawa, S. PY - 2005 DA - 2005// TI - Folate, vitamin B6, vitamin B12, and vitamin B2 intake, genetic polymorphisms of related enzymes, and risk of colorectal cancer in a hospital-based case-control study in Japan JO - Nutr Cancer VL - 53 UR - https://doi.org/10.1207/s15327914nc5301_5 DO - 10.1207/s15327914nc5301_5 ID - Otani2005 ER - TY - JOUR AU - Graessmann, M. AU - Berg, B. AU - Fuchs, B. AU - Klein, A. AU - Graessmann, A. PY - 2007 DA - 2007// TI - Chemotherapy resistance of mouse WAP-SVT/t breast cancer cells is mediated by osteopontin, inhibiting apoptosis downstream of caspase-3 JO - Oncogene VL - 26 UR - https://doi.org/10.1038/sj.onc.1210096 DO - 10.1038/sj.onc.1210096 ID - Graessmann2007 ER - TY - JOUR AU - Oleinik, N. V. AU - Krupenko, N. I. AU - Krupenko, S. A. PY - 2011 DA - 2011// TI - Epigenetic silencing of ALDH1L1, a metabolic regulator of cellular proliferation, in cancers JO - Genes Cancer VL - 2 UR - https://doi.org/10.1177/1947601911405841 DO - 10.1177/1947601911405841 ID - Oleinik2011 ER - TY - JOUR AU - Clarhaut, J. AU - Fraineau, S. AU - Guilhot, J. AU - Peraudeau, E. AU - Tranoy-Opalinski, I. AU - Thomas, M. PY - 2013 DA - 2013// TI - A galactosidase-responsive doxorubicin-folate conjugate for selective targeting of acute myelogenous leukemia blasts JO - Leuk Res VL - 37 UR - https://doi.org/10.1016/j.leukres.2013.04.026 DO - 10.1016/j.leukres.2013.04.026 ID - Clarhaut2013 ER - TY - JOUR AU - Luca, P. AU - Vazquez, E. S. AU - Moiola, C. P. AU - Zalazar, F. AU - Cotignola, J. AU - Gueron, G. PY - 2011 DA - 2011// TI - BRCA1 loss induces GADD153-mediated doxorubicin resistance in prostate cancer JO - Mol Cancer Res VL - 9 UR - https://doi.org/10.1158/1541-7786.MCR-11-0155 DO - 10.1158/1541-7786.MCR-11-0155 ID - Luca2011 ER - TY - JOUR AU - Meiyanto, E. AU - Fitriasari, A. AU - Hermawan, A. AU - Junedi, S. AU - Susidarti, R. PY - 2011 DA - 2011// TI - The improvement of doxorubicin activity on breast cancer cell lines by tangeretin through cell cycle modulation JO - Orient Pharm Exp Med VL - 11 UR - https://doi.org/10.1007/s13596-011-0016-4 DO - 10.1007/s13596-011-0016-4 ID - Meiyanto2011 ER - TY - JOUR AU - Petruccelli, L. A. AU - Dupere-Richer, D. AU - Pettersson, F. AU - Retrouvey, H. AU - Skoulikas, S. AU - Miller, W. H. PY - 2011 DA - 2011// TI - Vorinostat induces reactive oxygen species and DNA damage in acute myeloid leukemia cells JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0020987 DO - 10.1371/journal.pone.0020987 ID - Petruccelli2011 ER - TY - JOUR AU - Lanzi, C. AU - Cassinelli, G. AU - Cuccuru, G. AU - Supino, R. AU - Zuco, V. AU - Ferlini, C. PY - 2001 DA - 2001// TI - Cell cycle checkpoint efficiency and cellular response to paclitaxel in prostate cancer cells JO - Prostate VL - 48 UR - https://doi.org/10.1002/pros.1105 DO - 10.1002/pros.1105 ID - Lanzi2001 ER - TY - JOUR AU - Kerley-Hamilton, J. S. AU - Pike, A. M. AU - Li, N. AU - DiRenzo, J. AU - Spinella, M. J. PY - 2005 DA - 2005// TI - A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embryonal carcinoma JO - Oncogene VL - 24 UR - https://doi.org/10.1038/sj.onc.1208755 DO - 10.1038/sj.onc.1208755 ID - Kerley-Hamilton2005 ER - TY - JOUR AU - Li, J. AU - Wood, W. H. AU - Becker, K. G. AU - Weeraratna, A. T. AU - Morin, P. J. PY - 2007 DA - 2007// TI - Gene expression response to cisplatin treatment in drug-sensitive and drug-resistant ovarian cancer cells JO - Oncogene VL - 26 UR - https://doi.org/10.1038/sj.onc.1210086 DO - 10.1038/sj.onc.1210086 ID - Li2007 ER - TY - JOUR AU - D’Atri, S. AU - Graziani, G. AU - Lacal, P. M. AU - Nistico, V. AU - Gilberti, S. AU - Faraoni, I. PY - 2000 DA - 2000// TI - Attenuation of O(6)-methylguanine-DNA methyltransferase activity and mRNA levels by cisplatin and temozolomide in jurkat cells JO - J Pharmacol Exp Ther VL - 294 ID - D’Atri2000 ER - TY - JOUR AU - Adusumilli, P. S. AU - Chan, M. K. AU - Chun, Y. S. AU - Hezel, M. AU - Chou, T. C. AU - Rusch, V. W. PY - 2006 DA - 2006// TI - Cisplatin-induced GADD34 upregulation potentiates oncolytic viral therapy in the treatment of malignant pleural mesothelioma JO - Cancer Biol Ther VL - 5 UR - https://doi.org/10.4161/cbt.5.1.2237 DO - 10.4161/cbt.5.1.2237 ID - Adusumilli2006 ER - TY - JOUR AU - Fishel, M. L. AU - Rabik, C. A. AU - Bleibel, W. K. AU - Li, X. AU - Moschel, R. C. AU - Dolan, M. E. PY - 2006 DA - 2006// TI - Role of GADD34 in modulation of cisplatin cytotoxicity JO - Biochem Pharmacol VL - 71 UR - https://doi.org/10.1016/j.bcp.2005.10.039 DO - 10.1016/j.bcp.2005.10.039 ID - Fishel2006 ER - TY - JOUR AU - Lamb, J. AU - Crawford, E. D. AU - Peck, D. AU - Modell, J. W. AU - Blat, I. C. AU - Wrobel, M. J. PY - 2006 DA - 2006// TI - The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease JO - Science VL - 313 UR - https://doi.org/10.1126/science.1132939 DO - 10.1126/science.1132939 ID - Lamb2006 ER - TY - JOUR AU - Minotti, G. AU - Menna, P. AU - Salvatorelli, E. AU - Cairo, G. AU - Gianni, L. PY - 2004 DA - 2004// TI - Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity JO - Pharmacol Rev VL - 56 UR - https://doi.org/10.1124/pr.56.2.6 DO - 10.1124/pr.56.2.6 ID - Minotti2004 ER - TY - JOUR AU - Li, H. AU - Lu, Y. AU - Piao, L. AU - Wu, J. AU - Liu, S. AU - Marcucci, G. PY - 2010 DA - 2010// TI - Targeting human clonogenic acute myelogenous leukemia cells via folate conjugated liposomes combined with receptor modulation by all-trans retinoic acid JO - Int J Pharm VL - 402 UR - https://doi.org/10.1016/j.ijpharm.2010.09.019 DO - 10.1016/j.ijpharm.2010.09.019 ID - Li2010 ER - TY - JOUR AU - Moreira, M. P. AU - Silva, L. M. AU - Martins, W. K. PY - 2009 DA - 2009// TI - The role of GADD45A in resistance to oxidative stress-mediated cell death in human colon tumor cell lines JO - Applied Cancer Research VL - 29 ID - Moreira2009 ER - TY - JOUR AU - Lee, M. J. AU - Ye, A. S. AU - Gardino, A. K. AU - Heijink, A. M. AU - Sorger, P. K. AU - MacBeath, G. PY - 2012 DA - 2012// TI - Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks JO - Cell VL - 149 UR - https://doi.org/10.1016/j.cell.2012.03.031 DO - 10.1016/j.cell.2012.03.031 ID - Lee2012 ER - TY - JOUR AU - Azad, N. AU - Zahnow, C. A. AU - Rudin, C. M. AU - Baylin, S. B. PY - 2013 DA - 2013// TI - The future of epigenetic therapy in solid tumours—lessons from the past JO - Nat Rev Clin Oncol VL - 10 UR - https://doi.org/10.1038/nrclinonc.2013.42 DO - 10.1038/nrclinonc.2013.42 ID - Azad2013 ER - TY - JOUR AU - Fuller, M. AU - Klein, M. AU - Schmidt, E. AU - Rohde, C. AU - Gollner, S. AU - Schulze, I. PY - 2015 DA - 2015// TI - 5-azacytidine enhances efficacy of multiple chemotherapy drugs in AML and lung cancer with modulation of CpG methylation JO - Int J Oncol VL - 46 ID - Fuller2015 ER - TY - JOUR AU - Irizarry, R. A. AU - Hobbs, B. AU - Collin, F. AU - Beazer-Barclay, Y. D. AU - Antonellis, K. J. AU - Scherf, U. PY - 2003 DA - 2003// TI - Exploration, normalization, and summaries of high density oligonucleotide array probe level data JO - Biostatistics VL - 4 UR - https://doi.org/10.1093/biostatistics/4.2.249 DO - 10.1093/biostatistics/4.2.249 ID - Irizarry2003 ER - TY - JOUR AU - Watkins, D. AU - Rosenblatt, D. S. PY - 2012 DA - 2012// TI - Update and new concepts in vitamin responsive disorders of folate transport and metabolism JO - J Inherit Metab Dis VL - 35 UR - https://doi.org/10.1007/s10545-011-9418-1 DO - 10.1007/s10545-011-9418-1 ID - Watkins2012 ER - TY - JOUR AU - Fiorito, G. AU - Guarrera, S. AU - Valle, C. AU - Ricceri, F. AU - Russo, A. AU - Grioni, S. PY - 2014 DA - 2014// TI - B-vitamins intake, DNA-methylation of one carbon metabolism and homocysteine pathway genes and myocardial infarction risk: the EPICOR study JO - Nutr Metab Cardiovasc Dis VL - 24 UR - https://doi.org/10.1016/j.numecd.2013.10.026 DO - 10.1016/j.numecd.2013.10.026 ID - Fiorito2014 ER - TY - JOUR AU - Metayer, C. AU - Scelo, G. AU - Chokkalingam, A. P. AU - Barcellos, L. F. AU - Aldrich, M. C. AU - Chang, J. S. PY - 2011 DA - 2011// TI - Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia JO - Cancer Causes Control VL - 22 UR - https://doi.org/10.1007/s10552-011-9795-7 DO - 10.1007/s10552-011-9795-7 ID - Metayer2011 ER - TY - JOUR AU - Cheray, M. AU - Pacaud, R. AU - Nadaradjane, A. AU - Vallette, F. M. AU - Cartron, P. F. PY - 2013 DA - 2013// TI - Specific inhibition of one DNMT1-including complex influences tumor initiation and progression JO - Clin Epigenetics VL - 5 UR - https://doi.org/10.1186/1868-7083-5-9 DO - 10.1186/1868-7083-5-9 ID - Cheray2013 ER - TY - JOUR AU - Zhang, J. AU - Gao, Q. AU - Li, P. AU - Liu, X. AU - Jia, Y. AU - Wu, W. PY - 2011 DA - 2011// TI - S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance JO - Cell Res VL - 21 UR - https://doi.org/10.1038/cr.2011.176 DO - 10.1038/cr.2011.176 ID - Zhang2011 ER - TY - JOUR AU - Kanehisa, M. AU - Goto, S. PY - 2000 DA - 2000// TI - KEGG: Kyoto Encyclopedia of Genes and Genomes JO - Nucleic Acids Res VL - 28 UR - https://doi.org/10.1093/nar/28.1.27 DO - 10.1093/nar/28.1.27 ID - Kanehisa2000 ER - TY - JOUR AU - Stelzer, G. AU - Dalah, I. AU - Stein, T. I. AU - Satanower, Y. AU - Rosen, N. AU - Nativ, N. PY - 2011 DA - 2011// TI - In-silico human genomics with GeneCards JO - Hum Genomics VL - 5 UR - https://doi.org/10.1186/1479-7364-5-6-709 DO - 10.1186/1479-7364-5-6-709 ID - Stelzer2011 ER - TY - STD TI - OMIM®: Online Mendelian Inheritance in Man®. An Online Catalog of Human Genes and Genetic Disorders. 2015. Available from: http://omim.org. Accessed: 27 Feb 2015 UR - http://omim.org ID - ref125 ER - TY - JOUR AU - Griffith, M. AU - Griffith, O. L. AU - Coffman, A. C. AU - Weible, J. V. AU - McMichael, J. F. AU - Spies, N. C. PY - 2013 DA - 2013// TI - DGIdb: mining the druggable genome JO - Nat Methods VL - 10 UR - https://doi.org/10.1038/nmeth.2689 DO - 10.1038/nmeth.2689 ID - Griffith2013 ER - TY - JOUR AU - Whirl-Carrillo, M. AU - McDonagh, E. M. AU - Hebert, J. M. AU - Gong, L. AU - Sangkuhl, K. AU - Thorn, C. F. PY - 2012 DA - 2012// TI - Pharmacogenomics knowledge for personalized medicine JO - Clin Pharmacol Ther VL - 92 UR - https://doi.org/10.1038/clpt.2012.96 DO - 10.1038/clpt.2012.96 ID - Whirl-Carrillo2012 ER - TY - JOUR AU - Duan, Q. AU - Flynn, C. AU - Niepel, M. AU - Hafner, M. AU - Muhlich, J. L. AU - Fernandez, N. F. PY - 2014 DA - 2014// TI - LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures JO - Nucleic Acids Res VL - 42 UR - https://doi.org/10.1093/nar/gku476 DO - 10.1093/nar/gku476 ID - Duan2014 ER - TY - JOUR AU - Clark, N. R. AU - Hu, K. S. AU - Feldmann, A. S. AU - Kou, Y. AU - Chen, E. Y. AU - Duan, Q. PY - 2014 DA - 2014// TI - The characteristic direction: a geometrical approach to identify differentially expressed genes JO - BMC Bioinformatics VL - 15 UR - https://doi.org/10.1186/1471-2105-15-79 DO - 10.1186/1471-2105-15-79 ID - Clark2014 ER - TY - BOOK AU - Ma’ayan, A. AU - Duan, Q. PY - 2016 DA - 2016// TI - L1000CDS2: LINCS L1000 Characteristic Direction Signature Search Engine ID - Ma’ayan2016 ER - TY - JOUR AU - Benjamini, Y. AU - Hochberg, Y. PY - 1995 DA - 1995// TI - Controlling the false discovery rate: a practical and powerful approach to multiple testing JO - J R Statist Soc VL - B.57 ID - Benjamini1995 ER -