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Table 1 Differentially methylated regions (DMR). Shown are the DMRs with the significance level p < 0.05 as reported by the bumphunter software and spanning at least three CpGs with the average DNA methylation differences (delta beta) between IUGR and healthy twins above 10 % by magnitude in all CpGs. The DMRs are sorted by the magnitude of delta-beta differences. DMR length is measured in basepairs. Gene matches represent the overlaps between the DMR and the gene’s body or promoter region up to 1500 bp from the transcription start site. Genome coordinates are given with respect to hg19 genome assembly

From: Genome-wide placental DNA methylation analysis of severely growth-discordant monochorionic twins reveals novel epigenetic targets for intrauterine growth restriction

Chr Start End Δβ p value CpGs Length Gene
8 91013426 91013697 0.175 0.0027 6 272 DECR1
5 150284416 150284796 0.161 0.0032 7 381 ZNF300
15 78556834 78556945 −0.152 0.0082 5 112 DNAJA4
5 43396953 43397288 −0.139 0.0081 6 336 CCL28
1 65991176 65991664 0.133 0.0329 3 489 LEPR
6 31783322 31783482 0.130 0.0069 7 161 HSPA1A/L
10 106014615 106014893 0.126 0.0401 3 279 GSTO1
9 36258114 36258885 0.120 0.0114 6 772 GNE