Table 1 Sample characteristics
From: Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus
| Â | Â | Without complication (control) | With complication | Â | ||||
|---|---|---|---|---|---|---|---|---|
Hypertension | PE | p value | ||||||
|  |  | N = 15 | N = 11 | N = 36 |  | |||
Diagnostic criteria | Systolic blood pressure (max) | 130 | IQR 122–134 | 160 | IQR 148–170 | 175.5 | IQR 157–183 |  |
|  | Diastolic blood pressure (max) | 82 | IQR 77–85 | 98 | IQR 93–108 | 103 | IQR 98–115.5 |  |
| Â | Proteinuria | Â | Â | Â | Â | |||
| Â | Negative/trace | 15 | 11 | 6 | Â | |||
| Â | 1+ | 0 | 0 | 13 | Â | |||
| Â | 2+ | 0 | 0 | 8 | Â | |||
| Â | >3+ | 0 | 0 | 9 | Â | |||
Characteristics | Maternal age (year, mean ± SD) | 27.3 ± 3.3 | 26 ± 6.0 | 26.6 ± 6.1 | 0.8413 | |||
(Mother and fetus) | Week of gestation (median) | 39.3 | IQR 39.1–40.2 | 39.2 | IQR 37.4–39.5 | 39 | IQR 37.4–39.4 | 0.0191 |
|  | Weight at birth (g, mean ± SD) | 3454.3 ± .96 | 3097.3 ± 606.8 | 2931.1 ± 767.3 | 0.0566 | |||
| Â | Race | Â | Â | Â | 0.58 | |||
|  |  Black | 4 | 2 | 11 |  | |||
|  |  Hispanic | 5 | 6 | 19 |  | |||
|  |  White | 1 | 1 | 4 |  | |||
|  |  Other | 3 | 2 | 1 |  | |||
| Â | Declined | 2 | 0 | 1 | Â | |||
| Â | Sex (male, n) | 5 | 8 | 15 | 0.120 | |||
| Â | NSVD (n) | 5 | 8 | 15 | 0.120 | |||
| Â | Primiparous (n) | 3 | 6 | 24 | 0.016 | |||
| Â | Smoked (n) | 0 | 0 | 2 | 0.999 | |||
| Â | History of PE (n) | 0 | 2 | 5 | 0.242 | |||
Comorbidities (n) | Anemia | 4 | 1 | 5 | 0.502 | |||
(Mother) | Asthma | 1 | 3 | 5 | 0.419 | |||
|  | Obese (BMI > 30) | 4 | 4 | 17 | 0.401 | |||
| Â | GDM | 1 | 0 | 7 | 0.289 | |||
| Â | Chronic hypertension | 0 | 1 | 4 | 0.453 | |||
| Â | Migraines | 1 | 2 | 3 | 0.607 | |||
Medication (n) | Hypertensive drug prescribed | 0 | 1 | 9 | 0.006 | |||
(Mother) | MgSO4 administration | 0 | 6 | 25 | <0.0001 | |||