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Table 3 Crude and adjust odds ratios (ORs) and corresponding 95 % confidence intervals (CIs) for predictors of CIN3+ in cervical cancer

From: Combined clinical and genetic testing algorithm for cervical cancer diagnosis

  Odds ratio (95 % CI)
Variable Number Crude P value Adjusted P value
Age group
<30 52 Reference   Reference  
30–50 319 3.93 (1.72–9.00) 0.001 2.97 (1.13–7.80) 0.027
>50 78 4.02 (1.61–10.06) 0.003 2.13 (0.68–6.69) 0.194
No. of pregnancies
0 24 Reference    
1~3 232 2.68 (0.89–8.11) 0.081   
>3 193 3.04 (1.00–9.25) 0.050   
No. of births
0 46 Reference   Reference  
1~3 363 2.24 (1.05–4.79) 0.038 1.06 (0.43–2.63) 0.895
>3 40 4.54 (1.75–11.83) 0.002 1.71 (0.53–5.56) 0.370
Intrauterine device (IUD) usage
No 215 Reference    
Yes 234 1.41 (0.95–2.08) 0.087   
Condom usage
No 336 Reference   Reference  
Yes 113 0.59 (0.37–0.94) 0.027 0.78 (0.46–1.31) 0.349
Oral contraception usage
No 391 Reference    
Yes 58 0.81 (0.45–1.46) 0.478   
Tubal ligation
No 360 Reference    
Yes 89 0.98 (0.60–1.60) 0.937   
Gynecology history: cervical contact bleeding
No 329 Reference   Reference  
Yes 120 1.61 (1.05–2.47) 0.030 1.11 (0.68–1.80) 0.673
Gynecology history: vaginal bleeding
No 385 Reference   Reference  
Yes 64 3.77 (2.18–6.54) <0.001 2.95 (1.62–5.39) <0.001
Gynecology history: abnormal vaginal discharge
No 439 Reference    
Yes 10 1.87 (0.53–6.56) 0.329   
Gynecologic examination: grossly normal cervix
No 323 Reference   Reference  
Yes 126 0.40 (0.25–0.65) <0.001 0.51 (0.30–0.85) 0.011
Gynecologic examination : cervical erosion
No 196 Reference    
Yes 253 1.00 (0.68–1.48) 0.995   
Gynecologic examination: cervical mass
No 349 Reference   Reference  
Yes 100 2.01 (1.28–3.15) 0.003 1.37 (0.83–2.25) 0.220
Gynecologic examination: ulcer
No 446 Reference    
Yes 3 3.72 (0.33–41.33) 0.285   
Gynecologic examination: contact bleeding
No 403 Reference   Reference  
Yes 46 2.95 (1.58–5.50) 0.001 1.94 (0.99–3.83) 0.055