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Table 1 Population and test characteristics by histologic category

From: Combined clinical and genetic testing algorithm for cervical cancer diagnosis

   Histological results Total
  Cutoff Normal CIN1 CIN2 CIN3 CIS SCC/AC
Number of subjects
N (%)   218 (48.55) 30 (6.68) 43 (9.58) 72 (16.04) 15 (3.34) 71 (15.81) 449 (100)
Age (years)
Mean ± SD (range)   41.2 ± 10.6 (21.5 to 77.8) 47.0 ± 9.6 (29.0 to 66.2) 39.2 ± 11.1 (21.8 to 64.6) 37.3 ± 5.1 (23.7 to 63.0) 45.1 ± 8.7 (28.3 to 65.7) 42.9 ± 4.5 (32.5 to 74.3) 42.8 ± 10.3 (21.5 to 77.8)
Cytology results         
Normal (%)   90 (90.91) 4 (4.04) 2 (2.02) 0 (0.00) 1 (1.01) 2 (2.02) 99 (100)
ASC-US (%)   112 (53.85) 21 (10.10) 32 (15.38) 24 (11.54) 5 (2.40) 14 (6.73) 208 (100)
LSIL (%)   1 (16.67) 2 (33.33) 0 (0.00) 3 (50.00) 0 (0.00) 0 (0.00) 6 (100)
ASC-H/AGC/HSIL+ (%)   15 (11.03) 3 (2.21) 9 (6.62) 45 (33.09) 9 (6.62) 55 (40.44) 136 (100)
Detection modality or test used         
hrHPV (%)   100 (45.87) 18 (60.00) 39 (90.70) 71 (98.61) 15 (100) 69 (97.18) 312 (69.49)
HPV16/18 (%)   19 (8.72) 5 (16.67) 12 (27.91) 36 (50.00) 11 (73.33) 56 (78.87) 139 (30.96)
PAX1 m (%) ΔCp  9.0 34 (15.60) 4 (13.33) 15 (34.88) 47 (65.28) 11 (73.33) 52 (73.24) 163 (36.30)
ZNF582 m (%) ΔCp  11.0 22 (10.09) 6 (20.00) 10 (23.26) 48 (66.67) 12 (80.00) 61 (85.92) 159 (35.41)