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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Ultraviolet-B induces ERCC6 repression in lens epithelium cells of age-related nuclear cataract through coordinated DNA hypermethylation and histone deacetylation

Fig. 6

Protein level and promoter methylation status (site 8) of ERCC6 in HLE-B3 after treatment with UVB exposure. a 12 h after treatment with UVB exposure, the promoter of ERCC6 in the cells displayed hypermethylation compared to the control cells. *P < 0.01. b Protein levels of ERCC6 in control cells and in cells after treatment with UVB exposure. c Relative ERCC6 protein level to GAPDH is presented as mean ± SD. *P < 0.01. d Protein level of active caspases-3 in control cells and HLE-B3 cells after expose to UVB was measured by Western bolt analysis. e Relative active caspases-3 protein level to GAPDH is presented as mean ± SD. *P < 0.01

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Clinical Epigenetics

ISSN: 1868-7083

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