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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Ultraviolet-B induces ERCC6 repression in lens epithelium cells of age-related nuclear cataract through coordinated DNA hypermethylation and histone deacetylation

Fig. 5

The staining changes of ERCC6 and DNMT3b immunoreactivity in LECs of controls and ARNCs (Samples labeled as #16–#30 of the controls and #16–#30 of the ARNCs out of total 30 samples in each group). The LECs of controls showed low levels of DNMT3b and high levels of ERCC6 staining (a, c). DNMT3b immunoreactivity increased significantly and the ERCC6 immunoreactivity decreased significantly in LECs of ARNCs (b, d). Bar graph illustrated the immunoreactivity of ERCC6 and DNMT3b in LECs of controls and ARNCs (e). *P < 0.01. Scale bars: 50 μm

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Clinical Epigenetics

ISSN: 1868-7083

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