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Table 1 Distribution of socio-demographic variables and prevalent diseases at baseline among participants of the case cohort (ESTHER study 2000–2001)

From: Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort

Variable Survivors Cases within the subcohorta Cases outside the subcohortb
Sex    
 Female 721 (57.2) 113 (39.5) 138 (43.7)
 Men 539 (42.8) 173 (60.5) 178 (56.3)
Age    
 50–65 905 (71.8) 123 (43.0) 163 (51.6)
 66–75 355 (28.2) 163 (57.0) 153 (48.4)
Years of school education    
 >9 years 334 (27.0) 56 (20.4) 63 (20.5)
 ≤9 years 902 (73.0) 218 (80.6) 244 (79.5)
History of cancer disease    
 No 1201 (95.3) 254 (88.8) 268 (84.8)
 Yes 59 (4.7) 32 (11.1) 48 (15.2)
History of cardiovascular disease    
 No 1048 (83.2) 171 (59.8) 206 (65.2)
 Yes 212 (16.8) 115 (40.2) 110 (34.8)
Hypertension    
 No 714 (56.7) 142 (50.5) 154 (49.2)
 Yes 545 (43.3) 139 (49.5) 159 (50.8)
Diabetes mellitus    
 No 1068 (85.9) 216 (76.1) 227 (73.0)
 Yes 176 (14.2) 68 (23.9) 84 (27.0)
Body mass index (kg/m2)    
 <25 341 (27.1) 79 (27.6) 97 (30.7)
 25–<30 594 (47.1) 124 (43.4) 132 (41.8)
 ≥30 325 (25.8) 83 (29.0) 87 (27.5)
Smoking    
 Never/former 1034 (83.6) 203 (73.0) 233 (75.7)
 Current 203 (16.4) 75 (27.0) 75 (24.3)
  1. aParticipants of the randomly selected subcohort who were deceased during the follow-up (2000–2013)
  2. bParticipants specifically selected among deceased participants