Skip to main content
Fig. 1 | Clinical Epigenetics

Fig. 1

From: DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease

Fig. 1

a The pie chart shows differentially methylated probes in advanced versus mild fibrosis according to UCSC classification of CpG islands: Island (CpG island), N. Shore and shelf (2-kb upstream of CpG islands and 2–4-kb upstream of CpG islands, flanking regions of shores), Open Sea, S. Shore and shelf (2-kb downstream of CpG islands and flanking regions of shores). b Pie chart illustrates probes with methylation differences in advanced versus mild according to functional regions: TSS200 and 1500 (200- and 1500-bp upstream of transcription start sites; annotated promoters), 5′UTR (5′ untranslated region), 1st Exon, Gene body, 3′UTR (3′ untranslated region). c Pie charts show hypomethylated probes in advanced inflammation and fibrosis in comparison to mild fibrosis according to CpG clusters and functional regions. d Pie charts show hypermethylated probes in advanced inflammation and fibrosis in comparison to mild fibrosis according to CpG clusters and functional regions. ef Number and percentages of differentially methylated probes

Back to article page