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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Analysis of RET promoter CpG island methylation using methylation-specific PCR (MSP), pyrosequencing, and methylation-sensitive high-resolution melting (MS-HRM): impact on stage II colon cancer patient outcome

Fig. 3

Kaplan-Meier curves of overall survival for three years of follow-up. Patients with RET methylation (red line) measured by direct-MSP (a), nested-MSP (b), pyrosequencing with a threshold for positivity at 20 % (c), and MS-HRM (d) showed a trend towards a poorer prognosis; however, this was not statistically significant (p > 0.05)

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