Skip to main content

Table 1 Aberrantly methylated genes in ESCC

From: The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma

Gene Histological type (M%) Reference
HIN-1 LGD (31 %), MGD (33 %), HGD (44 %), ESCC (50 %) [111]
DAB2 Dysplasia (67 %), ESCC (68 %) [132]
PGP9.5 ESCC (42 %) [133]
ECRG4 ESCC (69 %) [134]
APC ESCC (50 %), EAC (92 %) [135]
FHIT ESCC (33 %) [24]
GNG7 ESCC (33 %) [136]
CDH1 ESCC (43 %) [137]
Integrin α4 ESCC (21 %) [137]
Wif-1 ESCC (35 %) [137]
MGMT LGD (23 %), MGD (17 %), HGD (11 %), ESCC (33 %) [44]
MLH1 LGD (8 %), MGD (17 %), HGD (33 %), ESCC (23 %) [44]
RARβ2 LGD (13 %), MGD (33 %), HGD (44 %), ESCC (36 %) [44]
TFPI-2 LGD (28 %), MGD (33 %), HGD (33 %), ESCC (67 %) [112]
DACH1 LGD (19 %), MGD and HGD (42 %), ESCC (62 %) [85]
SOX17 LGD (39 %), MGD and HGD (48 %), ESCC (65 %) [73]
DAPK LGD (28 %), MGD (25 %), HGD (11 %), ESCC (26 %) [44]
P16 LGD (31 %), MGD (42 %), HGD (33 %), ESCC (52 %) [44]
CHFR LGD (2.9 %), MGD (0), HGD (12.5 %), ESCC (45 %) [54]
RASSF10 ESCC (44.3 %) [49]
ZNF331 ESCC (56.5 %) [138]
  1. M% methylation rate, LGD low-grade dysplasia, MGD middle-grade dysplasia, HGD high-grade dysplasia, ESCC esophageal squamous carcinoma