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Table 3 Association between PAX6 methylation and clinicopathological characteristics of 160 HCC patients

From: Quantitative methylation analysis reveals distinct association between PAX6 methylation and clinical characteristics with different viral infections in hepatocellular carcinoma

Etiology All HBV HCV NBC
OR 95 % CI OR 95 % CI OR 95 % CI OR 95 % CI
Age 1.04 1.01–1.07 1.03 0.98–1.08 1.02 0.96–1.07 1.02 0.96–1.07
Gender 1.14 0.60–2.16 1.68 0.51–5.48 1.07 0.38–3.00 1.56 0.31–7.87
HBV 0.29 0.15–0.58       
HCV 4.46 2.26–8.80       
Cirrhosis 1.42 0.75–2.69 0.92 0.30–2.78 0.85 0.29–2.50 12.00 1.11–129.42
Tumor size (cm) 0.97 0.90–1.04 0.99 0.89–1.09 0.96 0.81–1.14 1.06 0.89–1.26
Nodules 1.01 0.84–1.20 0.97 0.74–1.27 1.02 0.33–3.11 1.49 0.91–2.44
TNM 1.02 0.72–1.43 1.36 0.74–2.50 0.89 0.48–1.65 1.68 0.75–3.78
AFP 1.24 0.61–2.51 1.17 0.32–4.25 1.46 0.46–4.65 1.00 0.21–4.71
Invasion 1.01 0.56–1.89 2.92 0.90–9.51 0.41 0.14–1.18 2.85 0.57–14.33
  1. OR odds ratio, 95 % CI 95 % confidence interval for the hazard ratio