Fig. 3

ROC curves for MGMT promoter methylation. Receiver operator characteristics (ROC) curve calculated on the basis of MGMT promoter methylation determined by MSP (orange line), HRM (blue line), PSQ (violet line), and age <70 (green line). ROC curves were calculated for (a) PFS ≥12 months and (b) OS ≥18 months. The area under the curve (AUC) corresponds to the prediction of survival, with a value of 1 indicating perfect discrimination, and a value of 0.5 no better than chance discrimination